SCHEMBL5086570

SCHEMBL5086570

COCCOCCOC(C)Br

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23291306 1.00 CA2 (0.32) CA2
SCHEMBL20745040 1.00 CA2 (0.32) CA2
SCHEMBL23291179 1.00 CA2 (0.32) CA2
SCHEMBL363919 0.92
SCHEMBL22208402 0.92
SCHEMBL22572326 0.89 MEN1 (0.30)
SCHEMBL22973142 0.80
SCHEMBL891978 0.79 LMNA (0.36) CA2
SCHEMBL20175910 0.79 CA2 (0.34) CA2
SCHEMBL10929539 0.79 CA2 (0.34) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4126229-A1 MTORC1 MODULATORS AND USES THEREOF Aeovian Pharmaceuticals, Inc. (US) 2023-02-08 EP disclosed
WO-2021195599-A1 MTORC1 MODULATORS AND USES THEREOF AEOVIAN PHARMACEUTICALS, INC. (US) 2021-09-30 WO disclosed
EP-3814356-A1 TRIAZOLOTRIAZINE DERIVATIVES AS A2A RECEPTOR ANTAGONISTS Zhejiang Vimgreen Pharmaceuticals, Ltd (CN) 2021-05-05 EP disclosed
EP-3186259-A1 TETRAHYDRONAPHTHALENE DERIVATIVES THAT INHIBIT MCL-1 PROTEIN Amgen Inc. (US) 2017-07-05 EP disclosed
WO-2016033486-A1 TETRAHYDRONAPHTHALENE DERIVATIVES THAT INHIBIT MCL-1 PROTEIN AMGEN INC. (US) 2016-03-03 WO disclosed
WO-2008037604-A1 NOVEL POLYBENZOFULVENE DERIVATIVES, SYNTHESIS AND USES THEREOF UNIVERSITÀ DEGLI STUDI DI SIENA (IT) 2008-04-03 WO disclosed
US-5194667-A Antistatic agents, fungicides or microbiocides for fibers ALLIED-SIGNAL INC. (US) 1993-03-16 US disclosed
US-4939289-A FUNGICIDES, MICROBIOCIDES, ANTISTATIC AGENTS, POLYAMIDES, POLYESTERS ALLIED-SIGNAL INC. (US) 1990-07-03 US disclosed