Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL5088373 | 1.00 | FDPS (0.42) | FDPSOPRM1SPHK1LMNADNM1 | |
| Iodide SCHEMBL5087651 | 1.00 | FDPS (0.42) | FDPSOPRM1SPHK1LMNADNM1 | |
| Iodide SCHEMBL5092873 | 1.00 | FDPS (0.42) | FDPSOPRM1SPHK1LMNADNM1 | |
| Iodide SCHEMBL5093335 | 1.00 | FDPS (0.42) | FDPSOPRM1SPHK1LMNADNM1 | |
| Iodide SCHEMBL5091402 | 1.00 | FDPS (0.42) | FDPSOPRM1SPHK1LMNADNM1 | |
| Iodide SCHEMBL5086849 | 1.00 | FDPS (0.42) | FDPSOPRM1SPHK1LMNADNM1 | |
| Iodide SCHEMBL5091780 | 1.00 | FDPS (0.42) | FDPSOPRM1SPHK1LMNADNM1 | |
| Iodide SCHEMBL5088501 | 0.98 | OPRM1 (0.42) | FDPSOPRM1SPHK1LMNADNM1 | |
| SCHEMBL331848 | 0.98 | FDPS (0.44) | FDPSOPRM1SPHK1LMNADNM1 | |
| SCHEMBL414859 | 0.98 | FDPS (0.44) | FDPSOPRM1SPHK1LMNADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |