Hydrochloric Acid

Hydrochloric Acid

SCHEMBL5087046

CCCC[P+](C)(C)CCCC.[Cl-]

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.53
TSHR P16473 4/20 0.47
THRB P10828 1/20 0.47
OPRM1 P35372 1/20 0.43
LMNA P02545 2/20 0.40
SPHK1 Q9NYA1 1/20 0.40
ALDH1A1 P00352 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
CYP3A4 P08684 1/20 0.38
FDPS P14324 1/20 0.38
ADH1B P00325 1/20 0.37
ADH1C P00326 1/20 0.37
ADH1A P07327 1/20 0.37
ADH4 P08319 1/20 0.37
ADH7 P40394 1/20 0.37
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL11520091 0.93 DNM1 (0.53) DNM1TSHRTHRBOPRM1LMNA
Iodide SCHEMBL5088425 0.93 DNM1 (0.53) DNM1TSHRTHRBOPRM1LMNA
Bromide SCHEMBL5088150 0.93 DNM1 (0.58) DNM1TSHRTHRBOPRM1LMNA
Hydrochloric Acid SCHEMBL5087047 0.90 DNM1 (0.58) DNM1TSHRTHRBOPRM1LMNA
Hydrochloric Acid SCHEMBL5086847 0.90 DNM1 (0.58) DNM1TSHRTHRBOPRM1LMNA
Hydrochloric Acid SCHEMBL23576227 0.90 DNM1 (0.58) DNM1TSHRTHRBOPRM1LMNA
Hydrochloric Acid SCHEMBL5088313 0.90 DNM1 (0.58) DNM1TSHRTHRBOPRM1LMNA
Hydrochloric Acid SCHEMBL5091937 0.90 DNM1 (0.58) DNM1TSHRTHRBOPRM1LMNA
Hydrochloric Acid SCHEMBL5087250 0.90 DNM1 (0.58) DNM1TSHRTHRBOPRM1LMNA
Hydrochloric Acid SCHEMBL7556604 0.90 DNM1 (0.58) DNM1TSHRTHRBOPRM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080214386-A1 Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2008-09-04 US disclosed
US-4052426-A FROM TIN OR ALLOY AND METHYL CHLORIDE, ALKYLPHOSPHONIUM CHLORIDE-TIN CHLORIDE COMPLEX CATALYST CIBA-GEIGY CORPORATION (US) 1977-10-04 US disclosed