Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.75 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.75 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.75 |
| ▸ | DPP4 | P27487 | 1/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2864514 | 0.89 | DPP4 (0.68) | SLC6A3SLC6A4SLC6A2DPP4S1PR1 | |
| Hydrochloric Acid SCHEMBL10669389 | 0.87 | DPP4 (0.66) | SLC6A3SLC6A4SLC6A2DPP4S1PR1 | |
| SCHEMBL10208913 | 0.87 | DPP4 (0.70) | SLC6A3SLC6A4SLC6A2DPP4S1PR1 | |
| SCHEMBL3516310 | 0.86 | SLC6A3 (1.00) | SLC6A3SLC6A4SLC6A2DPP4MAOA | |
| Hydrochloric Acid SCHEMBL5312403 | 0.82 | SLC6A4 (0.59) | SLC6A3SLC6A4SLC6A2DPP4S1PR1 | |
| SCHEMBL17906490 | 0.80 | SLC6A3 (0.89) | SLC6A3SLC6A4SLC6A2DPP4MAOA | |
| SCHEMBL29374849 | 0.79 | MAOA (0.68) | SLC6A3SLC6A4SLC6A2DPP4MAOA | |
| SCHEMBL11524018 | 0.79 | SLC6A4 (0.63) | SLC6A3SLC6A4SLC6A2DPP4S1PR1 | |
| SCHEMBL5090597 | 0.79 | SLC6A3 (0.73) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL5086410 | 0.79 | SLC6A3 (0.56) | SLC6A3SLC6A4SLC6A2DPP4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976513-A2 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | Sepracor, Inc. (US) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007081857-A2 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | SEPRACOR INC. (US) | 2007-07-19 | — | — | WO | disclosed |