Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL508712 | 0.92 | KCNH2 (0.42) | KCNH2PGR | |
| SCHEMBL508856 | 0.81 | KCNH2 (0.44) | KCNH2PGR | |
| SCHEMBL1347124 | 0.78 | KCNH2 (0.42) | KCNH2PGR | |
| SCHEMBL1347126 | 0.78 | KCNH2 (0.51) | KCNH2PGR | |
| SCHEMBL508714 | 0.77 | KCNH2 (0.40) | KCNH2PGR | |
| SCHEMBL5226673 | 0.76 | KCNH2 (0.47) | KCNH2PGR | |
| SCHEMBL5224343 | 0.76 | KCNH2 (0.49) | KCNH2PGR | |
| Lersivirine SCHEMBL508446 | 0.76 | KCNH2 (0.49) | KCNH2PGR | |
| SCHEMBL509696 | 0.75 | PGR (0.48) | KCNH2PGR | |
| SCHEMBL10250855 | 0.75 | KCNH2 (0.36) | KCNH2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120029192-A1 | Pyrazole Derivatives | PFIZER INC | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029192-A1 | Pyrazole Derivatives | POLRMT, PDCD11, DPYD | KCNH2 3548/4885PGR 891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.