Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 4/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.77 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.75 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5087826 | 1.00 | SLC22A1 (0.81) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL5088296 | 1.00 | SLC22A1 (0.81) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL864781 | 1.00 | SLC22A1 (0.81) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL5084910 | 1.00 | SLC22A1 (0.81) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL11830036 | 1.00 | SLC22A1 (0.81) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL5092856 | 1.00 | SLC22A1 (0.81) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL11143581 | 1.00 | SLC22A1 (0.81) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL22263450 | 1.00 | SLC22A1 (0.81) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL22263423 | 1.00 | SLC22A1 (0.81) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL11673043 | 1.00 | SLC22A1 (0.81) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961425-B2 | Viscous water-based composition | KAO CORPORATION (JP) | 2021-03-30 | — | — | US | disclosed |
| CN-107531941-B | Viscous water-based composition | 花王株式会社 | 2021-03-12 | — | — | CN | disclosed |
| EP-3275931-B1 | VISCOUS WATER-BASED COMPOSITION | KAO CORP (JP) | 2020-10-14 | — | — | EP | disclosed |
| CN-107840347-B | Titanium-silicon molecular sieve and preparation method and application thereof | 中国石油化工股份有限公司 | 2020-08-18 | — | — | CN | disclosed |
| CN-107840344-B | Titanium-silicon molecular sieve and preparation method and application thereof | 中国石油化工股份有限公司 | 2020-08-18 | — | — | CN | disclosed |
| CN-107840346-B | A kind of application of the preparation method of silica zeolite, processing method and silica zeolite, catalyst and catalyst | 中国石油化工股份有限公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-107840345-B | A kind of application of the preparation method of silica zeolite, processing method and silica zeolite, catalyst and catalyst | 中国石油化工股份有限公司 | 2019-07-19 | — | — | CN | disclosed |
| US-20180118991-A1 | VISCOUS WATER-BASED COMPOSITION | KAO CORPORATION (JP) | 2018-05-03 | — | — | US | disclosed |
| CN-107840347-A | A kind of HTS and its preparation method and application | 中国石油化工股份有限公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-107840348-A | The preparation method and mesopore molecular sieve and catalyst of a kind of mesopore molecular sieve | 中国石油化工股份有限公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-107840345-A | A kind of application of the preparation method of silica zeolite, processing method and silica zeolite, catalyst and catalyst | 中国石油化工股份有限公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-107840344-A | A kind of HTS and its preparation method and application | 中国石油化工股份有限公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-107840346-A | A kind of application of the preparation method of silica zeolite, processing method and silica zeolite, catalyst and catalyst | 中国石油化工股份有限公司 | 2018-03-27 | — | — | CN | disclosed |
| EP-3275931-A1 | VISCOUS WATER-BASED COMPOSITION | Kao Corporation (JP) | 2018-01-31 | — | — | EP | disclosed |
| CN-107531941-A | Viscous water-based composition | 花王株式会社 | 2018-01-02 | — | — | CN | disclosed |
| CN-101503508-B | Method for preparing polythiofuran in water-based medium | UNIV BEIJING NORMAL | 2011-02-16 | — | — | CN | disclosed |
| CN-101503508-A | Method for preparing polythiofuran in water-based medium | UNIV BEIJING NORMAL (CN) | 2009-08-12 | — | — | CN | disclosed |
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10961425-B2 | Viscous water-based composition | POLL, MYO1G, POLG | SLC22A1 3602/4885ALDH1A1 4758/4885TP53 960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.