⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18245212 | 0.85 | — | — | |
| SCHEMBL11421488 | 0.70 | — | — | |
| SCHEMBL9323168 | 0.70 | — | — | |
| SCHEMBL276850 | 0.64 | — | — | |
| SCHEMBL1252498 | 0.64 | — | — | |
| SCHEMBL186479 | 0.64 | — | — | |
| SCHEMBL28947049 | 0.64 | — | — | |
| Ethylenediamine SCHEMBL10527046 | 0.62 | — | — | |
| SCHEMBL18245458 | 0.62 | TSHR (0.35) | — | |
| SCHEMBL28896771 | 0.60 | LMNA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298736-B1 | Hydrazine-based and carbonyl-based bifunctional crosslinking reagents | SOLULINK INC (US) | 2015-07-15 | — | — | EP | disclosed |
| EP-2295407-B1 | Hydrazine-based and carbonyl-based bifunctional crosslinking reagents | SOLULINK INC (US) | 2014-11-05 | — | — | EP | disclosed |
| US-7462689-B2 | Hydrazine-based and carbonyl-based bifunctional crosslinking reagents | SOLULINK BIOSCIENCES, INC. (US) | 2008-12-09 | — | — | US | disclosed |
| US-6800728-B2 | CROSSLINKING AND IMMOBILIZING BIOMOLECULES, DRUGS AND SYNTHETIC POLYMERS WITH A THIOL OR AMINO REACTIVE GROUP AND HYDRAZINO OR OXYAMINO MOIETIES | SOLULINK BIOSCIENCES, INC. | 2004-10-05 | — | — | US | disclosed |
| EP-1315699-A2 | HYDRAZINE-BASED AND CARBONYL-BASED BIFUNCTIONAL CROSSLINKING REAGENTS | Solulink, Incorporated (US) | 2003-06-04 | — | — | EP | disclosed |
| US-20030013857-A1 | Hydrazine-based and carbonyl-based bifunctional crosslinking reagents | SOLULINK INCORPORATED | 2003-01-16 | — | — | US | disclosed |
| WO-2001070685-A2 | HYDRAZINE-BASED AND CARBONYL-BASED BIFUNCTIONAL CROSSLINKING REAGENTS | SOLULINK, INCORPORATED (US) | 2001-09-27 | — | — | WO | disclosed |