Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 4/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.77 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.75 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL5088074 | 1.00 | SLC22A1 (0.81) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| Iodide SCHEMBL8438836 | 1.00 | SLC22A1 (0.81) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| Iodide SCHEMBL5087906 | 1.00 | SLC22A1 (0.81) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| Iodide SCHEMBL5084907 | 1.00 | SLC22A1 (0.81) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| Iodide SCHEMBL5087935 | 1.00 | SLC22A1 (0.81) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| Iodide SCHEMBL5091301 | 1.00 | SLC22A1 (0.81) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| Iodide SCHEMBL5092140 | 1.00 | SLC22A1 (0.81) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| Iodide SCHEMBL5091439 | 1.00 | SLC22A1 (0.81) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| Iodide SCHEMBL5086846 | 1.00 | SLC22A1 (0.81) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 | |
| Iodide SCHEMBL5085196 | 1.00 | SLC22A1 (0.81) | SLC22A1ALDH1A1TP53CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |
| WO-2008024026-A2 | USE OF 9-OXOACRIDINE-10-ACETIC ACID, ITS SALTS AND ESTERS FOR THE TREATMENT, PROPHYLAXIS OR RELAPSE PREVENTION OF PROSTATE CANCER | SURKOV KIRILL GENNADIEVICH (RU) | 2008-02-28 | — | — | WO | disclosed |
| EP-1217011-B1 | Process for producing an expoxidized polymer | KURARAY CO (JP) | 2005-10-12 | — | — | EP | disclosed |
| US-20050104042-A1 | Process for the synthesis of amine ethers from secondary amino oxides | CIBA SPECIALTY CHEMICALS CORP. | 2005-05-19 | — | — | US | disclosed |
| EP-1463717-A2 | PROCESS FOR THE SYNTHESIS OF AMINE ETHERS FROM SECONDARY AMINO OXIDES AND USES | Ciba SC Holding AG (CH) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003045919-A2 | PROCESS FOR THE SYNTHESIS OF AMINE ETHERS FROM SECONDARY AMINO OXIDES AND USES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-06-05 | — | — | WO | disclosed |
| US-6541575-B2 | Epoxidation of polymer having olefinic carbon-carbon double in absence of alkali metal by adding aqueous solution of ammonium tungstate and/or tungstophosphoric acid and phosphoric acid, adding hydrogen peroxide and quternary ammonium salt | KURARAY CO., LTD. (JP) | 2003-04-01 | — | — | US | disclosed |
| US-20020082348-A1 | Process for producing an epoxidized polymer | KURARAY CO. LTD, (JP) | 2002-06-27 | — | — | US | disclosed |
| EP-1217011-A1 | Process for producing an expoxidized polymer | KURARAY CO., LTD. (JP) | 2002-06-26 | — | — | EP | disclosed |
| EP-0532861-B1 | Method for producing a carbonic acid ester | MITSUBISHI CHEM CORP (JP) | 1996-05-01 | — | — | EP | disclosed |
| US-5227510-A | 2-Hydroxypyridine Complexes | MITSUBISHI KASEI CORPORATION (JP) | 1993-07-13 | — | — | US | disclosed |
| EP-0532861-A1 | Method for producing a carbonic acid ester | Mitsubishi Chemical Corporation (JP) | 1993-03-24 | — | — | EP | disclosed |
| EP-0149246-B1 | OVERCOAT COMPOSITIONS CONTAINING NUCLEATING AGENTS AND ION-SELECTIVE ELECTRODES FOR CO2 DETERMINATIONS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1990-02-28 | — | — | EP | disclosed |
| EP-0033707-B1 | ELEMENT FOR LIQUID ANALYSIS HAVING INTERFERENT-REMOVAL ZONE AND METHOD FOR USING SAME | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1984-06-20 | — | — | EP | disclosed |
| EP-0030503-B1 | BUFFER OVERCOAT FOR CO2 ION-SELECTIVE ELECTRODES | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1984-05-09 | — | — | EP | disclosed |
| US-4303408-A | EXTRACTION ZONE BEFORE INDICATOR ZONE | EASTMAN KODAK COMPANY (US) | 1981-12-01 | — | — | US | disclosed |
| EP-0033707-A1 | Element for liquid analysis having interferent-removal zone and method for using same | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1981-08-12 | — | — | EP | disclosed |
| EP-0030503-A1 | Buffer overcoat for CO2 ion-selective electrodes | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1981-06-17 | — | — | EP | disclosed |
| US-4272328-A | MULTILAYER, METALS, METAL HALIDES | EASTMAN KODAK COMPANY (US) | 1981-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050104042-A1 | Process for the synthesis of amine ethers from secondary amino oxides | AOC2, PPOX, DAO | SLC22A1 4540/4885ALDH1A1 1566/4885TP53 2333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.