Sugi Predict

Sugi Predict / Compounds / Fluorene

Fluorene

Fluorene

SCHEMBL5087300

C1=CCC=C1.c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 3/20 0.52
▸ KDM4E B2RXH2 2/20 0.48
▸ NPC1 O15118 2/20 0.48
▸ MAPT P10636 2/20 0.48
▸ RAB9A P51151 2/20 0.48
▸ SMN1; SMN2 Q16637 2/20 0.48
▸ ALDH1A1 P00352 2/20 0.48
▸ LMNA P02545 1/20 0.48
▸ HPGD P15428 1/20 0.48
▸ CYP1A2 P05177 3/20 0.44
▸ CYP3A4 P08684 2/20 0.44
▸ BCHE P06276 1/20 0.43
▸ CES1 P23141 1/20 0.43
▸ SRD5A2 P31213 1/20 0.42
▸ PLK4 O00444 1/20 0.41
▸ DAPK3 O43293 1/20 0.41
▸ PIM1 P11309 1/20 0.41
▸ PDGFRA P16234 1/20 0.41
▸ LTK P29376 1/20 0.41
▸ MAP2K2 P36507 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL28049914 0.98 MAOA (0.50) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL31261898 0.87 MAOA (0.65) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL27915067 0.84 MAOA (0.62) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL545861 0.84 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL29478468 0.84 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL29355380 0.84 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL8180 0.84 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL31388525 0.84 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL10626727 0.81 MAOA (0.65) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL8378972 0.81 MAOA (0.65) MAOAKDM4ENPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105367611-A Olefin high-temperature polymerization metallocene catalyst and preparation method thereof and application of olefin high-temperature polymerization metallocene catalyst in olefin polymerization UNIV EAST CHINA SCIENCE & TECH 2016-03-02 — — CN claimed
EP-3249707-B1 ORGANIC COMPOUND AND LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DIODE DISPLAY DEVICE USING THE SAME LG DISPLAY CO LTD (KR) 2023-11-22 — — EP disclosed
EP-3941923-B1 SYNTHESIS OF METALLOCENE POLYMERIZATION CATALYST NOVA CHEM INT SA (CH) 2023-07-12 — — EP disclosed
WO-2023011383-A1 COPOLYMER, AND PREPARATION METHOD THEREFOR AND USE THEREOF 华为技术有限公司 2023-02-09 — — WO disclosed
US-20220153771-A1 SYNTHESIS OF METALLOCENE POLYMERIZATION CATALYST NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2022-05-19 — — US disclosed
EP-3941923-A1 SYNTHESIS OF METALLOCENE POLYMERIZATION CATALYST Nova Chemicals (International) S.A. (CH) 2022-01-26 — — EP disclosed
WO-2020188473-A1 SYNTHESIS OF METALLOCENE POLYMERIZATION CATALYST NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2020-09-24 — — WO disclosed
CN-105367611-B A kind of olefin high-temperature polymerization metallocene catalyst and preparation method thereof and application in olefin polymerization 华东理工大学 2019-04-05 — — CN disclosed
CN-105367611-B A kind of olefin high-temperature polymerization metallocene catalyst and preparation method thereof and application in olefin polymerization 华东理工大学 2019-04-05 — — CN disclosed
CN-105367611-A Olefin high-temperature polymerization metallocene catalyst and preparation method thereof and application of olefin high-temperature polymerization metallocene catalyst in olefin polymerization UNIV EAST CHINA SCIENCE & TECH 2016-03-02 — — CN disclosed
CN-101029108-A Copolymerization of ethene and norbornene CHINA PETROCHEMICAL CORP (CN) 2007-09-05 — — CN disclosed
US-20070135598-A1 Supported metallocene catalysts and their use in producing stereospecific polymers FINA TECHNOLOGY, INC. 2007-06-14 — — US disclosed
US-7211536-B2 Supported metallocene catalysts and their use in producing stereospecific polymers FINA TECHNOLOGY, INC. (US) 2007-05-01 — — US disclosed
US-20060089470-A1 Supported metallocene catalysts and their use in producing stereospecific polymers FINA TECHNOLOGY, INC. 2006-04-27 — — US disclosed
CN-1105118-C Method for producing high melting-point polyolefins BAYER AG (DE) 2003-04-09 — — CN disclosed
CN-1100799-C Method for producing cycloolefin or (CO) polymers for industrial applications BAYER AG (DE) 2003-02-05 — — CN disclosed
CN-1282343-A Method for producing elastomers BAYER AG (DE) 2001-01-31 — — CN disclosed
CN-1229416-A Method for producing cycloolefin or (CO) polymers for industrial applications BAYER AG (DE) 1999-09-22 — — CN disclosed
CN-1229418-A Process for preparing high-melting polyolefin BAYER AG (DE) 1999-09-22 — — CN disclosed
EP-0537130-B1 Process and catalyst for producing isotactic polyolefins FINA TECHNOLOGY (US) 1996-09-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153771-A1 SYNTHESIS OF METALLOCENE POLYMERIZATION CATALYST AFF4, POTEE, KCNK13 MAOA 2495/4885KDM4E 16/4885NPC1 2771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.