Fluorene

Fluorene

SCHEMBL545861

c1ccc2c(c1)Cc1ccccc1-2.c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.68
KDM4E B2RXH2 2/20 0.61
NPC1 O15118 2/20 0.61
MAPT P10636 2/20 0.61
RAB9A P51151 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
ALDH1A1 P00352 1/20 0.61
LMNA P02545 1/20 0.61
HPGD P15428 1/20 0.61
CES1 P23141 2/20 0.55
BCHE P06276 1/20 0.55
SRD5A2 P31213 1/20 0.52
PLK4 O00444 1/20 0.50
DAPK3 O43293 1/20 0.50
PIM1 P11309 1/20 0.50
PDGFRA P16234 1/20 0.50
LTK P29376 1/20 0.50
MAP2K2 P36507 1/20 0.50
FLT3 P36888 1/20 0.50
MAPK8 P45983 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL8180 1.00 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL29355380 1.00 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL29478468 1.00 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL31388525 1.00 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL6739194 0.97 MAOA (0.65) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL8378972 0.97 MAOA (0.65) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL9435671 0.97 MAOA (0.65) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL9791437 0.97 MAOA (0.65) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL1080516 0.97 MAOA (0.65) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL10626727 0.97 MAOA (0.65) MAOAKDM4ENPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080200736-A1 MATERIAL FOR ORGANIC LIGHT-EMITTING ELEMENT AND ORGANIC LIGHT-EMITTING ELEMENT INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2008-08-21 US claimed
EP-0035011-B1 GRAPHITE COMPOSITION UBBELOHDE, Alfred Rene John Paul (GB) 1984-04-25 EP claimed
EP-0035011-A1 GRAPHITE COMPOSITION. UBBELOHDE ALFRED R J P 1981-09-09 EP claimed
WO-1980002552-A1 GRAPHITE COMPOSITION UBBELOHDE A 1980-11-27 WO claimed
US-4213956-A Granite composition UBBELOHDE ALFRED R J P 1980-07-22 US claimed
EP-3994196-A1 LIGHT-EMITTING COMPOSITION Sumitomo Chemical Co., Ltd (JP) 2022-05-11 EP disclosed
CN-114072447-A Luminescent composition 住友化学株式会社 2022-02-18 CN disclosed
CN-215310238-U Solvent recovery device for producing 9, 9-bis [4- (2-hydroxyethoxy) phenyl ] fluorene 江苏永星化工股份有限公司 2021-12-28 CN disclosed
WO-2021001663-A1 LIGHT-EMITTING COMPOSITION SUMITOMO CHEMICAL CO., LTD (JP) 2021-01-07 WO disclosed
CN-105607422-B Alkali-soluble resin, photosensitive resin composition containing same and application 奇美实业股份有限公司 2019-11-12 CN disclosed
CN-110128323-A A kind of fluorenes simultaneously carbazole derivates, preparation method and application 武汉尚赛光电科技有限公司 2019-08-16 CN disclosed
CN-110036010-A INHIBITORS OF KRAS G12C MUTANT PROTEINS 亚瑞克西斯制药公司 2019-07-19 CN disclosed
CN-1561872-A Method for producing diacetate fiber tows of chitosan modified cigarette UNIV JIANGNAN (CN) 2005-01-12 CN disclosed
US-5902907-A VAPOR PHASE CATALYTIC OXIDATION OF FLUORENE WITH OXYGEN-CONTAINING GAS IN PRESENCE OF CATALYST CONTAINING METAL ELEMENT OF GROUP 5 OR 6, HAVING MOLAR RATIO OF FLUORENE TO OXYGEN WITHIN SPECIFIED RANGE NIPPON SHOKUBAI CO., LTD. (JP) 1999-05-11 US disclosed
US-5712085-A PLATELET STORAGE CERUS CORPORATION (US) 1998-01-27 US disclosed
US-5600958-A Shipper HENNING STEVE (US) 1997-02-11 US disclosed
EP-0035011-B1 GRAPHITE COMPOSITION UBBELOHDE, Alfred Rene John Paul (GB) 1984-04-25 EP disclosed
EP-0035011-A1 GRAPHITE COMPOSITION. UBBELOHDE ALFRED R J P 1981-09-09 EP disclosed
WO-1980002552-A1 GRAPHITE COMPOSITION UBBELOHDE A 1980-11-27 WO disclosed
US-4213956-A Granite composition UBBELOHDE ALFRED R J P 1980-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080200736-A1 MATERIAL FOR ORGANIC LIGHT-EMITTING ELEMENT AND ORGANIC LIGHT-EMITTING ELEMENT INCLUDING THE SAME LEF1, FMNL1, AFF1 MAOA 717/4885KDM4E 4091/4885NPC1 1155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.