Bromide

Bromide

SCHEMBL5087893

CCCCCCCCCCC[n+]1ccn(C)c1.[Br-]

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 1/20 0.52
CHRM4 known ✓ P08173 1/20 0.52
CHRM5 known ✓ P08912 1/20 0.52
CHRM1 known ✓ P11229 1/20 0.52
CHRM3 known ✓ P20309 1/20 0.52
ACHE known ✓ P22303 1/20 0.52
HSP90AA1 P07900 2/20 0.52
RAD52 P43351 2/20 0.52
EGFR P00533 1/20 0.52
LMNA P02545 1/20 0.52
PLA2G1B P04054 1/20 0.52
ERBB2 P04626 1/20 0.52
LCK P06239 1/20 0.52
FYN P06241 1/20 0.52
ADRA2A P08913 1/20 0.52
ADORA3 P0DMS8 1/20 0.52
TSHR P16473 1/20 0.52
ALOX12 P18054 1/20 0.52
ADRA2B P18089 1/20 0.52
ADRA2C P18825 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL3189755 1.00 HSP90AA1 (0.52) HSP90AA1RAD52EGFRLMNAPLA2G1B
Bromide SCHEMBL5084956 1.00 HSP90AA1 (0.52) HSP90AA1RAD52EGFRLMNAPLA2G1B
Bromide SCHEMBL193063 1.00 HSP90AA1 (0.52) HSP90AA1RAD52EGFRLMNAPLA2G1B
Bromide SCHEMBL5091782 1.00 HSP90AA1 (0.52) HSP90AA1RAD52EGFRLMNAPLA2G1B
Bromide SCHEMBL574727 1.00 HSP90AA1 (0.52) HSP90AA1RAD52EGFRLMNAPLA2G1B
Bromide SCHEMBL466201 1.00 HSP90AA1 (0.52) HSP90AA1RAD52EGFRLMNAPLA2G1B
Bromide SCHEMBL5091686 1.00 HSP90AA1 (0.52) HSP90AA1RAD52EGFRLMNAPLA2G1B
Bromide SCHEMBL28475500 1.00 HSP90AA1 (0.52) HSP90AA1RAD52EGFRLMNAPLA2G1B
Bromide SCHEMBL5087802 1.00 HSP90AA1 (0.52) HSP90AA1RAD52EGFRLMNAPLA2G1B
Bromide SCHEMBL2890412 1.00 HSP90AA1 (0.52) HSP90AA1RAD52EGFRLMNAPLA2G1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080214386-A1 Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2008-09-04 US disclosed