Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.52 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.52 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.52 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.52 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.52 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.52 |
| ▸ | RAD52 | P43351 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3189755 | 1.00 | HSP90AA1 (0.52) | HSP90AA1RAD52EGFRLMNAPLA2G1B | |
| Bromide SCHEMBL5084956 | 1.00 | HSP90AA1 (0.52) | HSP90AA1RAD52EGFRLMNAPLA2G1B | |
| Bromide SCHEMBL5091782 | 1.00 | HSP90AA1 (0.52) | HSP90AA1RAD52EGFRLMNAPLA2G1B | |
| Bromide SCHEMBL5087893 | 1.00 | HSP90AA1 (0.52) | HSP90AA1RAD52EGFRLMNAPLA2G1B | |
| Bromide SCHEMBL574727 | 1.00 | HSP90AA1 (0.52) | HSP90AA1RAD52EGFRLMNAPLA2G1B | |
| Bromide SCHEMBL466201 | 1.00 | HSP90AA1 (0.52) | HSP90AA1RAD52EGFRLMNAPLA2G1B | |
| Bromide SCHEMBL5091686 | 1.00 | HSP90AA1 (0.52) | HSP90AA1RAD52EGFRLMNAPLA2G1B | |
| Bromide SCHEMBL28475500 | 1.00 | HSP90AA1 (0.52) | HSP90AA1RAD52EGFRLMNAPLA2G1B | |
| Bromide SCHEMBL5087802 | 1.00 | HSP90AA1 (0.52) | HSP90AA1RAD52EGFRLMNAPLA2G1B | |
| Bromide SCHEMBL2890412 | 1.00 | HSP90AA1 (0.52) | HSP90AA1RAD52EGFRLMNAPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 782 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078235-A1 | METHOD FOR POLYURETHANE DEPOLYMERIZATION | UNIV MURCIA (ES) | 2026-03-19 | — | — | US | claimed |
| US-20250188048-A1 | METHOD FOR PREPARING 2,5-FURANDICARBOXYLIC ACID COMPOUND | JIANGSU CELLURANICS NEW MATERIAL TECHNOLOGY CO., LTD. (CN) | 2025-06-12 | — | — | US | claimed |
| EP-4556514-A1 | METHOD FOR POLYURETHANE DEPOLYMERIZATION | Universidad de Murcia (ES) | 2025-05-21 | — | — | EP | claimed |
| CN-119193246-B | Cleaning agent for electric tea boiler of motor car and preparation method of cleaning agent | 广州市凯之达化工有限公司 | 2025-05-16 | — | — | CN | claimed |
| CN-119504596-A | Preparation method and application of functional lithium battery anode AT9 coating additive material | 安徽得壹能源科技有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-119193246-A | Cleaning agent for electric tea boiler of motor car and preparation method of cleaning agent | 广州市凯之达化工有限公司 | 2024-12-27 | — | — | CN | claimed |
| EP-4477651-A1 | METHOD FOR PREPARING 2,5-FURANDICARBOXYLIC ACID COMPOUND | Jiangsu Celluranics New Material Technology Co., Ltd. (CN) | 2024-12-18 | — | — | EP | claimed |
| CN-117945893-A | Method for separating succinic acid and adipic acid mixture | 开滦（集团）有限责任公司 | 2024-04-30 | — | — | CN | claimed |
| WO-2024013423-A1 | METHOD FOR POLYURETHANE DEPOLYMERIZATION | UNIVERSIDAD DE MURCIA (ES) | 2024-01-18 | — | — | WO | claimed |
| US-20240021887-A1 | ELECTROLYTE FOR AQUEOUS ZINC-BROMINE BATTERY CONTAINING BROMINE COMPLEXING AGENT AND METAL ION ADDITIVE, AND AQUEOUS ZINC-BROMINE NON-FLOW BATTERY CONTAINING SAME | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2024-01-18 | — | — | US | claimed |
| EP-2598661-A2 | COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN SALIVA AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES | Biomatrica, INC. (US) | 2013-06-05 | — | — | EP | claimed |
| US-8329022-B2 | Method for quantifying a chemical substance by substitutional stripping voltammetry and a sensor chip used therefor | PANASONIC CORPORATION (JP) | 2012-12-11 | — | — | US | claimed |
| US-20120216604-A1 | METHOD FOR QUANTIFYING A CHEMICAL SUBSTANCE BY SUBSTITUTIONAL STRIPPING VOLTAMMETRY AND A SENSOR CHIP USED THEREFOR | PANASONIC CORPORATION (JP) | 2012-08-30 | — | — | US | claimed |
| US-20120052572-A1 | COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN BLOOD AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES | EXACT SCIENCES CORPORATION | 2012-03-01 | — | — | US | claimed |
| WO-2012018639-A2 | COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN SALIVA AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES | BIOMATRICA, INC. (US) | 2012-02-09 | — | — | WO | claimed |
| WO-2012012047-A2 | PROCESS FOR PRODUCING TEREPHTHALIC ACID | UOP LLC (US) | 2012-01-26 | — | — | WO | claimed |
| WO-2012005902-A2 | PROCESS FOR PURIFYING TEREPHTHALIC ACID | UOP LLC (US) | 2012-01-12 | — | — | WO | claimed |
| US-20120004456-A1 | PROCESS FOR PURIFYING TEREPHTHALIC ACID | UOP LLC (US) | 2012-01-05 | — | — | US | claimed |
| US-20120004450-A1 | PROCESS FOR PRODUCING TEREPHTHALIC ACID | BORESKOV INSTITUTE OF CATALYSIS (RU) | 2012-01-05 | — | — | US | claimed |
| WO-2007134183-A2 | CHEMICAL REAGENT DELIVERY SYSTEM UTILIZING IONIC LIQUID STORAGE MEDIUM | ADVANCED TECHNOLOGY MATERIALS, INC. (US) | 2007-11-22 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250188048-A1 | METHOD FOR PREPARING 2,5-FURANDICARBOXYLIC ACID COMPOUND | HPD, DPYD, PGD | CHRM2 3380/4885CHRM4 2985/4885CHRM5 1730/4885 |
| US-20120052572-A1 | COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN BLOOD AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES | HNRNPD, HNRNPDL, HNRNPL | CHRM2 4853/4885CHRM4 4858/4885CHRM5 4842/4885 |
| US-20260078235-A1 | METHOD FOR POLYURETHANE DEPOLYMERIZATION | FGB, POLR2B, POLB | CHRM2 3826/4885CHRM4 4538/4885CHRM5 4177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.