Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 4/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5087985 | 0.90 | PDE1B (0.40) | CHRM4PDE1BSSTR2KMT2ANCF1 | |
| SCHEMBL5092297 | 0.82 | CHRM4 (0.41) | CHRM4KMT2AMEN1ALDH1A1NCF1 | |
| SCHEMBL5024502 | 0.82 | CHRM4 (0.41) | CHRM4KMT2AMEN1ALDH1A1NCF1 | |
| SCHEMBL5042661 | 0.78 | ALDH1A1 (0.43) | CHRM4KMT2AMEN1ALDH1A1NCF1 | |
| SCHEMBL5042666 | 0.78 | ALDH1A1 (0.43) | CHRM4KMT2AMEN1ALDH1A1NCF1 | |
| Hydrochloric Acid SCHEMBL5022641 | 0.78 | KMT2A (0.40) | CHRM4KMT2AMEN1ALDH1A1NCF1 | |
| Hydrochloric Acid SCHEMBL5040355 | 0.78 | ALDH1A1 (0.42) | CHRM4KMT2AMEN1ALDH1A1NCF1 | |
| Hydrochloric Acid SCHEMBL5022640 | 0.78 | KMT2A (0.40) | CHRM4KMT2AMEN1ALDH1A1NCF1 | |
| Hydrochloric Acid SCHEMBL5025459 | 0.78 | KMT2A (0.40) | CHRM4KMT2AMEN1ALDH1A1NCF1 | |
| Hydrochloric Acid SCHEMBL5040350 | 0.78 | ALDH1A1 (0.42) | CHRM4KMT2AMEN1ALDH1A1NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474145-B1 | QUINOLINE DERIVATIVES AS NPY ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2008-04-23 | — | — | EP | claimed |