Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
| ▸ | NCF1 | P14598 | 4/20 | 0.38 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5024502 | 1.00 | CHRM4 (0.41) | CHRM4KMT2AMEN1ALDH1A1NQO2 | |
| SCHEMBL5042666 | 0.87 | ALDH1A1 (0.43) | CHRM4KMT2AMEN1ALDH1A1NCF1 | |
| SCHEMBL5042661 | 0.87 | ALDH1A1 (0.43) | CHRM4KMT2AMEN1ALDH1A1NCF1 | |
| Hydrochloric Acid SCHEMBL5040350 | 0.86 | ALDH1A1 (0.42) | CHRM4KMT2AMEN1ALDH1A1NCF1 | |
| Hydrochloric Acid SCHEMBL5022640 | 0.86 | KMT2A (0.40) | CHRM4KMT2AMEN1ALDH1A1NCF1 | |
| Hydrochloric Acid SCHEMBL5022641 | 0.86 | KMT2A (0.40) | CHRM4KMT2AMEN1ALDH1A1NCF1 | |
| Hydrochloric Acid SCHEMBL5025459 | 0.86 | KMT2A (0.40) | CHRM4KMT2AMEN1ALDH1A1NCF1 | |
| Hydrochloric Acid SCHEMBL5040355 | 0.86 | ALDH1A1 (0.42) | CHRM4KMT2AMEN1ALDH1A1NCF1 | |
| SCHEMBL5087897 | 0.82 | CHRM4 (0.38) | CHRM4KMT2AMEN1ALDH1A1NCF1 | |
| SCHEMBL5022928 | 0.81 | HTR1A (0.45) | KMT2AMEN1ALDH1A1HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474145-B1 | QUINOLINE DERIVATIVES AS NPY ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2008-04-23 | — | — | EP | claimed |