Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP12A | P54707 | 5/20 | 0.81 |
| ▸ | ATP1A1 | P05023 | 4/20 | 0.81 |
| ▸ | ATP1B1 | P05026 | 4/20 | 0.81 |
| ▸ | ATP1A3 | P13637 | 4/20 | 0.81 |
| ▸ | ATP1B2 | P14415 | 4/20 | 0.81 |
| ▸ | ATP1A2 | P50993 | 4/20 | 0.81 |
| ▸ | ATP1B3 | P54709 | 4/20 | 0.81 |
| ▸ | FXYD2 | P54710 | 4/20 | 0.81 |
| ▸ | ATP1A4 | Q13733 | 4/20 | 0.81 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ADCY1 | Q08828 | 3/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cassaine SCHEMBL4167835 | 0.89 | ATP12A (1.00) | ATP12AATP1A1ATP1B1ATP1A3ATP1B2 | |
| Cassaine SCHEMBL4167834 | 0.89 | ATP12A (1.00) | ATP12AATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL30505265 | 0.87 | ATP1A1 (0.73) | ATP12AATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL4148208 | 0.87 | ATP1A1 (0.73) | ATP12AATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL6857608 | 0.87 | ATP1A1 (0.73) | ATP12AATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL6857605 | 0.87 | ATP1A1 (0.73) | ATP12AATP1A1ATP1B1ATP1A3ATP1B2 | |
| Cassaine SCHEMBL7805406 | 0.86 | ATP12A (0.93) | ATP12AATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL11892867 | 0.81 | ATP12A (0.84) | ATP12AATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL677461 | 0.81 | ATP12A (0.84) | ATP12AATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL5082160 | 0.79 | ATP1A1 (0.71) | ATP12AATP1A1ATP1B1ATP1A3ATP1B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115181-A9 | COMPOUNDS EXHIBITING EFFLUX INHIBITOR ACTIVITY AND COMPOSITIONS AND USES THEREOF | EASTMAN CHEM CO (US) | 2008-04-03 | — | — | WO | disclosed |
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | EASTMAN CHEMICAL COMPANY | 2007-11-01 | — | — | US | disclosed |
| WO-2007115181-A2 | COMPOUNDS EXHIBITING EFFLUX INHIBITOR ACTIVITY AND COMPOSITIONS AND USES THEREOF | EASTMAN CHEMICAL COMPANY (US) | 2007-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | ABCC4, NCOA4, NR4A3 | ATP12A 1039/4885ATP1A1 305/4885ATP1B1 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.