Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29979119 | 1.00 | XDH (0.52) | XDH | |
| SCHEMBL28483507 | 0.86 | XDH (0.52) | XDH | |
| SCHEMBL28283406 | 0.86 | XDH (0.52) | XDH | |
| SCHEMBL28283407 | 0.86 | XDH (0.55) | XDH | |
| SCHEMBL18251 | 0.85 | PNP (0.62) | XDH | |
| SCHEMBL1394088 | 0.84 | PNP (0.61) | XDH | |
| Cyanide SCHEMBL2694132 | 0.82 | PNP (0.58) | XDH | |
| SCHEMBL29561480 | 0.81 | XDH (0.56) | XDH | |
| SCHEMBL30101022 | 0.80 | PDE9A (0.54) | XDH | |
| SCHEMBL8145524 | 0.80 | POLA1 (0.65) | XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109417-A1 | MGMT INHIBITOR COMBINATIONS FOR THE TREATMENT OF NEOPLASTIC DISORDERS | CASE WESTERN RESERVE UNIVERSITY (US) | 2008-09-12 | — | — | WO | claimed |