Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 5/20 | 0.72 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.69 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1239368 | 0.97 | DNM1 (0.77) | DNM1SLC22A1SLC22A2TSHRALDH1A1 | |
| Bromide SCHEMBL10701064 | 0.93 | DNM1 (0.72) | DNM1SLC22A1SLC22A2TSHRALDH1A1 | |
| Bromide SCHEMBL622840 | 0.93 | DNM1 (0.78) | DNM1SLC22A1SLC22A2TSHRALDH1A1 | |
| SCHEMBL17800111 | 0.93 | DNM1 (0.72) | DNM1SLC22A1SLC22A2TSHRALDH1A1 | |
| Iodide SCHEMBL5086874 | 0.93 | SLC22A1 (0.69) | DNM1SLC22A1SLC22A2TSHRALDH1A1 | |
| Iodide SCHEMBL4333792 | 0.93 | SLC22A1 (0.69) | DNM1SLC22A1SLC22A2TSHRALDH1A1 | |
| Water SCHEMBL999491 | 0.93 | DNM1 (0.72) | DNM1SLC22A1SLC22A2TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL394062 | 0.93 | DNM1 (0.72) | DNM1SLC22A1SLC22A2TSHRALDH1A1 | |
| Fluoride Ion SCHEMBL31559159 | 0.93 | DNM1 (0.72) | DNM1SLC22A1SLC22A2TSHRALDH1A1 | |
| Tetrabuthylammonium SCHEMBL6242211 | 0.90 | SLC22A1 (0.75) | DNM1SLC22A1SLC22A2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112608258-A | Method for synthesizing 4,4' -dichlorodiphenyl sulfone by sulfoxide oxidation method | 江苏傲伦达科技实业股份有限公司 | 2021-04-06 | — | — | CN | claimed |
| CN-101402599-A | Bi(2,2,6,6-tetramethyl piperidine nitrogen oxygen free radical) ether ester and method of preparing the same | HUAIHAI INST TECHNOLOGY (CN) | 2009-04-08 | — | — | CN | claimed |
| CN-118239957-A | Process for the preparation of 2-exo- (2-methylbenzyloxy) -1-methyl-4-isopropyl-7-oxabicyclo [2.2.1] heptane | 巴斯夫农业公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-110337438-B | Process for the preparation of 2-exo- (2-methylbenzyloxy) -1-methyl-4-isopropyl-7-oxabicyclo [2.2.1] heptane | 巴斯夫农业公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-112608258-A | Method for synthesizing 4,4' -dichlorodiphenyl sulfone by sulfoxide oxidation method | 江苏傲伦达科技实业股份有限公司 | 2021-04-06 | — | — | CN | disclosed |
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |
| CN-1114834-A | antidiabetic agent | OTSUKA PHARMA CO LTD (JP) | 1996-01-10 | — | — | CN | disclosed |
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |
| US-4150057-A | ION EXCHANGING, REACTION OF BORON COMPOUND WITH DIMETHYL SULFIDE AND HYDROCHLORIC ACID | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1979-04-17 | — | — | US | disclosed |