Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.69 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.63 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL346989 | 0.97 | SLC22A1 (0.73) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| Bromide SCHEMBL3680180 | 0.93 | SLC22A1 (0.69) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| Iodide SCHEMBL5088044 | 0.93 | DNM1 (0.72) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| Water SCHEMBL1332993 | 0.93 | SLC22A1 (0.69) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL5084823 | 0.93 | SLC22A1 (0.69) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| SCHEMBL10598485 | 0.93 | SLC22A1 (0.69) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| Iodide SCHEMBL5086874 | 0.93 | SLC22A1 (0.69) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| SCHEMBL10598482 | 0.93 | SLC22A1 (0.69) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| Tetrabuthylammonium SCHEMBL6242211 | 0.90 | SLC22A1 (0.75) | SLC22A1DNM1SLC22A2TSHRALDH1A1 | |
| SCHEMBL11806867 | 0.90 | DNM1 (0.78) | SLC22A1DNM1SLC22A2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629491-B2 | Hydrocarboxylation process | EASTMAN CHEMICAL COMPANY (US) | 2009-12-08 | — | — | US | disclosed |
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |
| US-20070299280-A1 | forming propionic acid from ethylene, water and carbon monoxide; not using the hazardous and corrosive hydrogen halides or sulfonic acids; free of hydrogen iodide and/or ethyl iodide; no diethyl ketone by-products | EASTMAN CHEMICAL COMPANY (US) | 2007-12-27 | — | — | US | disclosed |
| US-4859389-A | Process for preparing polyamide fibers having improved properties | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1989-08-22 | — | — | US | disclosed |
| EP-0268261-A1 | Process for producing 1-hydrocarbyl mercaptans | PHILLIPS PETROLEUM COMPANY (US) | 1988-05-25 | — | — | EP | disclosed |
| US-4701377-A | POLYCAPROLACTAM, POLYHEXAMETHYLENE ADIPAMIDE, AND/OR TETRAMETHYLENEADIPAMIDE; USED FOR RUBBER REINFORCEMENT | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1987-10-20 | — | — | US | disclosed |
| EP-0004606-B1 | PROCESS FOR PREPARING ANILINE COMPOUNDS | ETHYL CORPORATION (US) | 1982-03-10 | — | — | EP | disclosed |
| US-4186147-A | DISPLACEMENT OF THIOCYANOANILINE WITH AN ALCOHOL TO FORM THIOALKYL ANILINE | ETHYL CORPORATION (US) | 1980-01-29 | — | — | US | disclosed |
| EP-0004606-A2 | Process for preparing aniline compounds | ETHYL CORPORATION (US) | 1979-10-17 | — | — | EP | disclosed |
| US-4022816-A | TRIALKYL AMMONIUM OR PHOSPHONIUM CATALYST | ETHYL CORPORATION (US) | 1977-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299280-A1 | forming propionic acid from ethylene, water and carbon monoxide; not using the hazardous and corrosive hydrogen halides or sulfonic acids; free of hydrogen iodide and/or ethyl iodide; no diethyl ketone by-products | ETV6, ETV1, HAO2 | SLC22A1 2340/4885DNM1 985/4885SLC22A2 2106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.