Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL925089 | 0.98 | DNM1 (0.59) | DNM1KDM4EALDH1A1TDP1MEN1 | |
| Water SCHEMBL27613448 | 0.95 | HTT (0.58) | DNM1KDM4EALDH1A1TDP1MEN1 | |
| Hydrochloric Acid SCHEMBL139563 | 0.95 | ALDH1A1 (0.62) | DNM1KDM4EALDH1A1TDP1MEN1 | |
| Hydrochloric Acid SCHEMBL14762882 | 0.95 | ALDH1A1 (0.62) | DNM1KDM4EALDH1A1TDP1MEN1 | |
| Water SCHEMBL2959266 | 0.95 | DNM1 (0.57) | DNM1KDM4EALDH1A1TDP1MEN1 | |
| Bromide SCHEMBL4071102 | 0.95 | DNM1 (0.60) | DNM1KDM4EALDH1A1TDP1MEN1 | |
| Water SCHEMBL10667376 | 0.93 | HTT (0.61) | DNM1KDM4EALDH1A1TDP1MEN1 | |
| Ammonia Solution, Strong SCHEMBL27810167 | 0.93 | ALDH1A1 (0.60) | DNM1KDM4EALDH1A1TDP1MEN1 | |
| Hydrochloric Acid SCHEMBL27795002 | 0.93 | ALDH1A1 (0.60) | DNM1KDM4EALDH1A1TDP1MEN1 | |
| Hydrochloric Acid SCHEMBL8067974 | 0.91 | KDM4E (0.58) | DNM1KDM4EALDH1A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |
| US-4125628-A | FORMALDEHYDE, QUATERNARY AMMONIUM SALT | VINELAND LABORATORIES, INC. (US) | 1978-11-14 | — | — | US | disclosed |
| US-4022911-A | Disinfectant composition comprising a quaternary ammonium compound, a phenol, and formaldehyde | DAMON CORPORATION (US) | 1977-05-10 | — | — | US | disclosed |