Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7641669 | 0.75 | ASAH1 (0.56) | CES2 | |
| SCHEMBL1026829 | 0.73 | CYP1A2 (0.56) | FAAH | |
| SCHEMBL7599990 | 0.71 | P2RX7 (0.48) | CES2 | |
| SCHEMBL2989445 | 0.69 | CES2 (0.64) | CES2FAAHMEN1MAPK1KMT2A | |
| SCHEMBL23950441 | 0.69 | CES2 (0.64) | CES2FAAHMEN1MAPK1KMT2A | |
| SCHEMBL23950236 | 0.69 | CES2 (0.64) | CES2FAAHMEN1MAPK1KMT2A | |
| SCHEMBL23950237 | 0.69 | CES2 (0.64) | CES2FAAHMEN1MAPK1KMT2A | |
| SCHEMBL21448801 | 0.69 | CES2 (0.64) | CES2FAAHMEN1MAPK1KMT2A | |
| SCHEMBL14477972 | 0.69 | CES2 (0.64) | CES2FAAHMEN1MAPK1KMT2A | |
| SCHEMBL8773299 | 0.69 | CES2 (0.64) | CES2FAAHMEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1440064-B1 | PROCESS FOR THE PREPARATION OF (PYRIMIDIN-2-YL)METHYL KETONES | LONZA AG (CH) | 2008-05-07 | — | — | EP | claimed |
| EP-1440064-B1 | PROCESS FOR THE PREPARATION OF (PYRIMIDIN-2-YL)METHYL KETONES | LONZA AG (CH) | 2008-05-07 | — | — | EP | disclosed |
| EP-1440064-A1 | PROCESS FOR THE PREPARATION OF (PYRIMMIDIN-2-YL)METHYL KETONES | LONZA LTD. (CH) | 2004-07-28 | — | — | EP | disclosed |
| WO-2003033474-A1 | PROCESS FOR THE PREPARATION OF (PYRIMMIDIN-2-YL)METHYL KETONES | LONZA LTD. (CH) | 2003-04-24 | — | — | WO | disclosed |