SCHEMBL50886

SCHEMBL50886

CC(C)c1ccc(OO)c(Cl)c1C(C)C

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
GABRA1 P14867 2/20 0.32
GABRB1 P18505 2/20 0.32
LMNA P02545 2/20 0.31
SLC6A2 P23975 2/20 0.31
HTR2B P41595 2/20 0.31
THRB P10828 1/20 0.31
RORC P51449 1/20 0.31
TRPA1 O75762 1/20 0.31
CHRM1 P11229 1/20 0.31
ADRA1A P35348 1/20 0.31
FAAH O00519 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
GABRG2 P18507 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL51043 0.82 CA1 (0.40) CA1CA2CA7CA9GABRA1
SCHEMBL29494156 0.78 CA1 (0.34) CA1CA2CA7CA9GABRA1
SCHEMBL99127 0.78 CA1 (0.34) CA1CA2CA7CA9GABRA1
SCHEMBL7983115 0.77 CA1 (0.33) CA1CA2CA7CA9GABRA1
SCHEMBL16843332 0.77 KCNK3 (0.35) TRPV1
SCHEMBL9456438 0.74 LMNA (0.45) CA1CA2GABRA1GABRB1LMNA
SCHEMBL1877670 0.74 CA1 (0.34) CA1CA2CA7CA9GABRA1
SCHEMBL11811124 0.74 NCEH1 (0.33)
SCHEMBL9718632 0.73 CYP3A4 (0.39) CA1CA2GABRA1GABRB1LMNA
SCHEMBL35520 0.72 GABRA1 (0.46) CA1CA2GABRA1GABRB1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118335386-A Conductive particle, anisotropic conductive film and electrical connection structure 华为技术有限公司 2024-07-12 CN claimed
CN-117756993-A Preparation method of low-yellowness-index acrylonitrile-butadiene-styrene graft copolymer and ABS rubber powder 万华化学集团股份有限公司 2024-03-26 CN claimed
CN-115716890-A Method for synthesizing high-solid-content styrene-butadiene latex by using compound viscosity reducer in one-step method 山东京博中聚新材料有限公司 2023-02-28 CN claimed
CN-107746447-B Delayed tackifying polymer for profile control and preparation method thereof 中国石油化工股份有限公司 2020-04-07 CN claimed
US-4617359-A High molecular weight polyacrylamide synthesis THE GOODYEAR TIRE & RUBBER COMPANY (US) 1986-10-14 US claimed
CN-118335386-A Conductive particle, anisotropic conductive film and electrical connection structure 华为技术有限公司 2024-07-12 CN disclosed
CN-117756993-A Preparation method of low-yellowness-index acrylonitrile-butadiene-styrene graft copolymer and ABS rubber powder 万华化学集团股份有限公司 2024-03-26 CN disclosed
CN-115716890-A Method for synthesizing high-solid-content styrene-butadiene latex by using compound viscosity reducer in one-step method 山东京博中聚新材料有限公司 2023-02-28 CN disclosed
US-8127372-B2 Polyisoprene aqueous emulsion and a method to fabricate gloves and related products SHANGHAI SHENGDA MEDICAL APPLICATION CO. LTD. (CN) 2012-03-06 US disclosed
US-20100237541-A1 Polyisoprene aqueous emulsion and a method to fabricate gloves and related products SHANGHAI SHENGDA MEDICAL APPLICATION CO. LTD. (CN) 2010-09-23 US disclosed
EP-0194222-B1 PREPARATION OF POLYMERS CONTAINING PENDANT ISOCYANATE GROUPS AND DERIVATIVES THEREOF BY EMULSION COPOLYMERIZATION THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-03-10 EP disclosed
US-5191083-A Unsaturated monomers with pendant carbamate groups, stabilization of synthetic rubbers THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-03-02 US disclosed
EP-0203879-B1 FUNCTIONALIZED MONOMERS FROM 1-(1-ISOCYANATO-1-METHYLETHYL)-3 OR 4-(1-METHYLETHENYL) BENZENE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1990-05-02 EP disclosed
US-4853478-A ANTIDEGRADATION MONOMERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1989-08-01 US disclosed
US-4714772-A POLYMERIZABLE ANTIDEGRADANTS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-12-22 US disclosed
US-4694057-A Preparation of polymers containing pendant isocyanate groups and derivatives thereof by emulsion copolymerization THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-09-15 US disclosed
EP-0203879-A2 Functionalized monomers from 1-(1-isocyanato-1-methylethyl)-3 or 4-(1-methylethenyl) benzene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1986-12-03 EP disclosed
US-4617359-A High molecular weight polyacrylamide synthesis THE GOODYEAR TIRE & RUBBER COMPANY (US) 1986-10-14 US disclosed
EP-0194222-A2 Preparation of polymers containing pendant isocyanate groups and derivatives thereof by emulsion copolymerization THE GOODYEAR TIRE & RUBBER COMPANY (US) 1986-09-10 EP disclosed
US-4604439-A STABILIZERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1986-08-05 US disclosed