Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.58 |
| ▸ | PPARA | Q07869 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | IGF1R | P08069 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | TACR2 | P21452 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11970251 | 0.98 | PPARA (0.59) | SKP2PPARAKDM4ERAB9AMEN1 | |
| SCHEMBL2786932 | 0.86 | KDM4E (0.63) | SKP2KDM4ERAB9AMEN1POLB | |
| SCHEMBL272366 | 0.86 | KDM4E (0.68) | SKP2KDM4ERAB9AMEN1POLB | |
| SCHEMBL1256802 | 0.85 | KAT8 (0.57) | SKP2PPARAKDM4EIGF1RALOX15 | |
| SCHEMBL1315795 | 0.84 | KAT8 (0.59) | SKP2PPARAKDM4EIGF1RALOX15 | |
| SCHEMBL9586309 | 0.84 | KAT8 (0.59) | SKP2PPARAKDM4EIGF1RALOX15 | |
| SCHEMBL8937894 | 0.84 | KAT8 (0.59) | SKP2PPARAKDM4EIGF1RALOX15 | |
| SCHEMBL9001576 | 0.84 | KAT8 (0.59) | SKP2PPARAKDM4EIGF1RALOX15 | |
| SCHEMBL9376917 | 0.84 | KAT8 (0.59) | SKP2PPARAKDM4EIGF1RALOX15 | |
| SCHEMBL69580 | 0.82 | IGF1R (0.79) | PPARAKDM4ERAB9AIGF1RALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103491937-A | Oxidative dyeing composition comprising 1-hexyl/heptyl-4, 5-diaminopyrazole and 2-aminophenol and derivatives thereof | PROCTER & GAMBLE | 2014-01-01 | — | — | CN | claimed |
| US-8444709-B2 | Oxidative dyeing compositions comprising an 1-hexyl/heptyl-4,5-diaminopyrazole and a 2-aminophenol and derivatives thereof | THE PROCTER & GAMBLE COMPANY (US) | 2013-05-21 | — | — | US | claimed |
| WO-2013058816-A1 | OXIDATIVE DYEING COMPOSITIONS COMPRISING AN 1-HEXYL/HEPTYL-4,5-DIAMINOPYRAZOLE AND A 2-AMINOPHENOL AND DERIVATIVES THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2013-04-25 | — | — | WO | claimed |
| US-20120210519-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a 2-Aminophenol and Derivatives Thereof | WELLA OPERATIONS US, LLC | 2012-08-23 | — | — | US | claimed |
| US-8444709-B2 | Oxidative dyeing compositions comprising an 1-hexyl/heptyl-4,5-diaminopyrazole and a 2-aminophenol and derivatives thereof | THE PROCTER & GAMBLE COMPANY (US) | 2013-05-21 | — | — | US | disclosed |
| WO-2013058816-A1 | OXIDATIVE DYEING COMPOSITIONS COMPRISING AN 1-HEXYL/HEPTYL-4,5-DIAMINOPYRAZOLE AND A 2-AMINOPHENOL AND DERIVATIVES THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2013-04-25 | — | — | WO | disclosed |
| US-20120210519-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a 2-Aminophenol and Derivatives Thereof | WELLA OPERATIONS US, LLC | 2012-08-23 | — | — | US | disclosed |
| US-20070054899-A1 | Aromatase inhibitor compounds and uses thereof | PARALLEL WIRELESS, INC. | 2007-03-08 | — | — | US | disclosed |
| EP-1678170-A1 | USE OF A COMPOUND OF FORMULA (I) AS AN INHIBITOR OF AROMATASE FOR THERAPEUTIC PURPOSES AND COMPOUNDS OF FORMULA (1) THEREAS | Yang Ji Chemical Company Ltd. (KR) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005033104-A1 | USE OF A COMPOUND OF FORMULA (I) AS AN INHIBITOR OF AROMATASE FOR THERAPEUTIC PURPOSES AND COMPOUNDS OF FORMULA (1) THEREAS | YANG JI CHEMICAL COMPANY, LTD (KR) | 2005-04-14 | — | — | WO | disclosed |
| US-4778792-A | Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders | LABORATORIES NEGMA (FR) | 1988-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120210519-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a 2-Aminophenol and Derivatives Thereof | TYR, GPX4, TH | SKP2 731/4885PPARA 2384/4885KDM4E 1009/4885 |
| US-20070054899-A1 | Aromatase inhibitor compounds and uses thereof | CYP19A1, CYP17A1, HSD17B11 | SKP2 274/4885PPARA 209/4885KDM4E 742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.