Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.67 |
| ▸ | DHFR | P00374 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 7/20 | 0.57 |
| ▸ | RXRA | P19793 | 1/20 | 0.56 |
| ▸ | RXRB | P28702 | 1/20 | 0.56 |
| ▸ | RXRG | P48443 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.54 |
| ▸ | AGXT | P21549 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13577128 | 0.89 | MAOB (0.65) | MAOBDHFRMAOARXRARXRB | |
| SCHEMBL9627120 | 0.83 | MAOB (0.76) | MAOBDHFRMAOARXRARXRB | |
| SCHEMBL14860962 | 0.82 | MAOB (0.70) | MAOBDHFRMAOARXRARXRB | |
| SCHEMBL5087372 | 0.81 | MAOB (0.61) | MAOBDHFRMAOANR4A2 | |
| SCHEMBL30040891 | 0.81 | MAOB (0.63) | MAOBMAOACYP3A4 | |
| SCHEMBL4473165 | 0.81 | MAOB (0.63) | MAOBMAOACYP3A4 | |
| SCHEMBL5096517 | 0.81 | MAOB (0.62) | MAOBMAOAIDO1 | |
| SCHEMBL5089231 | 0.81 | MAOB (0.71) | MAOBMAOANR4A2IDO1AGXT | |
| SCHEMBL1680762 | 0.80 | MAOB (1.00) | MAOBDHFRMAOARXRARXRB | |
| Hydrochloric Acid SCHEMBL9124176 | 0.80 | MAOB (0.61) | MAOBMAOACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722929-B2 | N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators | VALEANT PHARMACEUTICALS INTERNATIONAL (US) | 2014-05-13 | — | — | US | disclosed |
| US-20080188561-A1 | N-[2-AMINO-4-(PHENYLMETHOXY)PHENYL] AMIDES AND RELATED COMPOUNDS AS POTASSIUM CHANNEL MODULATORS | JPMORGAN CHASE BANK, N.A. | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188561-A1 | N-[2-AMINO-4-(PHENYLMETHOXY)PHENYL] AMIDES AND RELATED COMPOUNDS AS POTASSIUM CHANNEL MODULATORS | KCNB2, KCNJ2, KCNA2 | MAOB 808/4885DHFR 2747/4885MAOA 1086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.