⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12691708 | 0.82 | — | — | |
| SCHEMBL30507223 | 0.76 | — | — | |
| SCHEMBL18170424 | 0.67 | — | — | |
| Bromoform SCHEMBL30113935 | 0.61 | — | — | |
| Isobutane SCHEMBL30203183 | 0.55 | — | — | |
| Isopropyl Alcohol SCHEMBL1955704 | 0.55 | — | — | |
| Isobutane SCHEMBL29666472 | 0.53 | — | — | |
| SCHEMBL1803530 | 0.53 | — | — | |
| SCHEMBL4352 | 0.49 | — | — | |
| Bromomethane SCHEMBL13032077 | 0.49 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025128873-A1 | HETEROCYCLIC PYRIDINONE COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | VIGIL NEUROSCIENCE, INC. (US) | 2025-06-19 | — | — | WO | disclosed |
| WO-2025067457-A1 | HETEROCYCLIC FUSED RING COMPOUND, AND COMPOSITION AND USE THEREOF | 深圳市塔吉瑞生物医药有限公司 | 2025-04-03 | — | — | WO | disclosed |
| EP-3603674-B1 | COMBINATION OF MORPHINAN COMPOUNDS AND ANTIDEPRESSANT FOR THE TREATMENT OF INTRACTABLE AND CHRONIC PAIN | SUN PHARMACEUTICAL IND INC (US) | 2025-02-26 | — | — | EP | disclosed |
| US-20230285387-A1 | COMBINATION OF MORPHINAN COMPOUNDS AND ANTIDEPRESSANT FOR THE TREATMENT OF PSEUDOBULBAR AFFECT, NEUROLOGICAL DISEASES, INTRACTABLE AND CHRONIC PAIN AND BRAIN INJURY | CONCERT PHARMACEUTICALS, INC. | 2023-09-14 | — | — | US | disclosed |
| US-20220023292-A1 | COMBINATION OF MORPHINAN COMPOUNDS AND ANTIDEPRESSANT FOR THE TREATMENT OF PSEUDOBULBAR AFFECT, NEUROLOGICAL DISEASES, INTRACTABLE AND CHRONIC PAIN AND BRAIN INJURY | CONCERT PHARMACEUTICALS, INC. | 2022-01-27 | — | — | US | disclosed |
| US-10813926-B2 | Morphinan compounds | CONCERT PHARMACEUTICALS, INC. (US) | 2020-10-27 | — | — | US | disclosed |
| EP-3603674-A1 | COMBINATION OF MORPHINAN COMPOUNDS AND ANTIDEPRESSANT FOR THE TREATMENT OF INTRACTABLE AND CHRONIC PAIN | CONCERT PHARMACEUTICALS, INC. (US) | 2020-02-05 | — | — | EP | disclosed |
| US-10406155-B2 | Morphinan compounds | CONCERT PHARMACEUTICALS, INC. (US) | 2019-09-10 | — | — | US | disclosed |
| EP-3248978-B1 | DEUTERATED MORPHINAN COMPOUNDS | CONCERT PHARMACEUTICALS INC (US) | 2019-08-07 | — | — | EP | disclosed |
| US-20190038618-A1 | MORPHINAN COMPOUNDS | SUN PHARMACEUTICAL INDUSTRIES, INC. | 2019-02-07 | — | — | US | disclosed |
| EP-2634187-A1 | Deuterated morphinane compounds | Concert Pharmaceuticals Inc. (US) | 2013-09-04 | — | — | EP | disclosed |
| EP-2334678-B1 | MORPHINAN COMPOUNDS | CONCERT PHARMACEUTICALS INC (US) | 2012-12-26 | — | — | EP | disclosed |
| US-20120244122-A1 | Peptides for the Treatment of HCV Infections | CONCERT PHARMACEUTICALS, INC. | 2012-09-27 | — | — | US | disclosed |
| US-20120083487-A1 | COMBINATION OF MORPHINAN COMPOUNDS AND ANTIDEPRESSANT FOR THE TREATMENT OF PSEUDOBULBAR AFFECT, NEUROLGICAL DISEASES, INTRACTABLE AND CHRONIC PAIN AND BRAIN INJURY | CONCERT PHARMACEUTICALS, INC. | 2012-04-05 | — | — | US | disclosed |
| EP-2418211-A1 | Deuterated morphinane compounds | Concert Pharmaceuticals Inc. (US) | 2012-02-15 | — | — | EP | disclosed |
| US-20120029007-A1 | MORPHINAN COMPOUNDS | CONCERT PHARMACEUTICALS INC. | 2012-02-02 | — | — | US | disclosed |
| EP-2397158-A2 | Combination of morphinan compounds and antidepressant for the treatment of pseudobulbar affect | CONCERT PHARMACEUTICALS, INC. (US) | 2011-12-21 | — | — | EP | disclosed |
| US-20110257214-A1 | MORPHINAN COMPOUNDS | SUN PHARMACEUTICAL INDUSTRIES, INC. | 2011-10-20 | — | — | US | disclosed |
| WO-2010138889-A1 | PEPTIDES FOR THE TREATMENT OF HCV INFECTIONS | CONCERT PHARMACEUTICALS, INC. (US) | 2010-12-02 | — | — | WO | disclosed |
| US-20090175824-A1 | Peptides for the treatment of HCV infections | CONCERT PHARMACEUTICALS, INC. | 2009-07-09 | — | — | US | disclosed |