SCHEMBL5089544

SCHEMBL5089544

C#Cc1ccc(-c2c(N)cccc2S)cc1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ EGLN2 Q96KS0 1/20 0.33
▸ CA12 O43570 1/20 0.32
▸ CA1 P00915 1/20 0.32
▸ CA2 P00918 1/20 0.32
▸ CA4 P22748 1/20 0.32
▸ CA9 Q16790 1/20 0.32
▸ CA14 Q9ULX7 1/20 0.32
▸ KEAP1 Q14145 1/20 0.32
▸ PTPRC P08575 1/20 0.32
▸ ADORA2A P29274 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31243103 0.77 ALDH1A1 (0.44) KEAP1PTPRCADORA2A
SCHEMBL5841832 0.77 ALDH1A1 (0.44) KEAP1PTPRCADORA2A
SCHEMBL5089542 0.75 EGLN2 (0.33) EGLN2CA12CA1CA2CA4
SCHEMBL29429038 0.69 ALDH1A1 (0.58) EGLN2CA12CA1CA2CA4
SCHEMBL4630043 0.69 ALDH1A1 (0.58) EGLN2CA12CA1CA2CA4
SCHEMBL6347456 0.69 EGLN2 (0.44) EGLN2CA12CA1CA2CA4
SCHEMBL18762688 0.69 EGLN2 (0.39) EGLN2CA12CA1CA2CA4
SCHEMBL28641386 0.69 CYP3A4 (0.35) KEAP1
SCHEMBL24254918 0.68 CYP3A4 (0.47) KEAP1PTPRCADORA2A
SCHEMBL11309110 0.67 TTR (0.47) EGLN2CA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7410868-B2 Method for fabricating a nonvolatile memory element and a nonvolatile memory element INFINEON TECHNOLOGIES AG (DE) 2008-08-12 — — US disclosed
US-20060234418-A1 Method for fabricating a nonvolatile memory element and a nonvolatile memory element POLARIS INNOVATIONS LIMITED (IE) 2006-10-19 — — US disclosed
US-20060175604-A1 Novel type of attachment of organic molecules to a silicon surface for producing memory elements having organic constituents INFINEON TECHNOLOGIES AG (DE) 2006-08-10 — — US disclosed
EP-1684304-A2 Binding of organic molecules to a silicon surface for fabrication of storage elements with organic compounds Infineon Technologies AG (DE) 2006-07-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060175604-A1 Novel type of attachment of organic molecules to a silicon surface for producing memory elements having organic constituents L1CAM, KCNN2, KCNN1 EGLN2 1908/4885CA12 438/4885CA1 60/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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