SCHEMBL5089575

SCHEMBL5089575

CC1(COC(F)(F)C(F)(F)C(F)C(F)F)COC1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8809630 0.83
SCHEMBL10202771 0.77 EPHX1 (0.37) EPHX1
SCHEMBL2869376 0.74 EPHX1 (0.34) EPHX1
SCHEMBL6759270 0.73 EPHX1 (0.35) EPHX1
SCHEMBL6763602 0.72 EPHX1 (0.33) EPHX1
SCHEMBL3434135 0.72 EPHX1 (0.39) EPHX1
SCHEMBL5088678 0.71 EPHX1 (0.32) EPHX1
SCHEMBL10264236 0.69 EPHX1 (0.37) EPHX1
SCHEMBL3695518 0.69 EPHX1 (0.37) EPHX1
SCHEMBL3695521 0.67 EPHX1 (0.38) EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5668250-A Polyether coprepolymers formed from mono-substituted fluorinated oxetane monomers and tetrahydrofuran AEROJET-GENERAL CORPORATION (US) 1997-09-16 US claimed
US-7354985-B2 Fluorinated thermoset polyurethane elastomers prepared from polyether prepolymers formed from mono-substituted fluorinated oxetane monomers AEROJET ROCKETDYNE, INC. (F/K/A AEROJET-GENERAL CORPORATION) 2008-04-08 US disclosed
US-7148309-B2 Amorphous polyether glycols based on bis-substituted oxetane monomers AMPAC FINE CHEMICALS LLC (US) 2006-12-12 US disclosed
EP-0811004-B1 MONO-SUBSTITUTED FLUORINATED OXETANE MONOMERS AEROJET GENERAL CO (US) 2006-12-06 EP disclosed
US-20060135729-A1 Amorphous polyether glycols based on bis-substituted oxetane monomers AEROJET-GENERAL CORPORATION (US) 2006-06-22 US disclosed
US-6998460-B2 Amorphous polyether glycols based on bis-substituted oxetane and tetrahydrofuran monomers AEROJET-GENERAL CORPORATION (US) 2006-02-14 US disclosed
US-20050154217-A1 Amorphous polyether glycols based on bis-substituted oxetane and tetrahydrofuran monomers AEROJET-GENERAL CORPORATION 2005-07-14 US disclosed
US-6891013-B1 Fluorinated polyurethane elastomers prepared from polyether prepolymers formed from mono-substituted fluorinated oxetane monomers and tetrahydrofuran AEROJET-GENERAL CORPORATION (US) 2005-05-10 US disclosed
US-6825316-B2 FOR MAKING A FLUORINATED POLYETHERURETHANE COPOLYMER ELASTOMER; TEFLON SIMILAR NONSTICK COATINGS, HYDROPHOBIC, LOW SURFACE ENERGIES, LOW GLASS TRANSITION TEMPERATURES, NONABRASIVE AND TEAR STRENGTH, ADHESION AEROJET-GENERAL CORPORATION 2004-11-30 US disclosed
US-20040087759-A1 Fluorinated thermoset polyurethane elastomers prepared from polyether prepolymers formed mono-substituted fluorinated oxetane monomers AEROJET ROCKETDYNE, INC. (F/K/A AEROJET-GENERAL CORPORATION) 2004-05-06 US disclosed
EP-0811004-A4 MONO-SUBSTITUTED FLUORINATED OXETANE MONOMERS AEROJET GENERAL CO (US) 1998-09-30 EP disclosed
US-5807977-A Polyoxetanes based on pendant perfluoroalkyl side chains such as 3-methyl-3-(2,2,2-trifluoroethoxymethyl)-oxetane to form polyethers; very low surface energy, high hydrophobicity, low glass transition temperature and low coefficient of friction AEROJET GENERAL CORPORATION (US) 1998-09-15 US disclosed
US-5703194-A WATERPROOFING; TEAR STRENGTH; BONDING STRENGTH AEROJET-GENERAL CORPORATION (US) 1997-12-30 US disclosed
EP-0811004-A1 MONO-SUBSTITUTED FLUORINATED OXETANE MONOMERS AEROJET-GENERAL CORPORATION (US) 1997-12-10 EP disclosed
US-5668250-A Polyether coprepolymers formed from mono-substituted fluorinated oxetane monomers and tetrahydrofuran AEROJET-GENERAL CORPORATION (US) 1997-09-16 US disclosed
US-5668251-A Preparation of co-prepolymers from mono-substituted fluorinated monomers and tetrahydrofuran AEROJET-GENERAL CORPORATION (US) 1997-09-16 US disclosed
US-5654450-A THERMOPLASTIC RESIN INTERMEDIATES; TEAR STRENGTH, ADHESION AEROJET-GENERAL CORPORATION (US) 1997-08-05 US disclosed
US-5650483-A PREPARING A SOLUTION OF A CATALYST, AN INITIATOR AND A SOLVENT, CONTACTING SOLUTION WITH A SECOND SOLUTION CONTAINING FLUORINATED OXETANE MONOMER(S) AND CONTROLLING THE TEMPERATURE OF THE MIXTURE AEROJET-GENERAL CORPORATION (US) 1997-07-22 US disclosed
US-5637772-A OIL REPELLENT COATINGS; ANTIFOULING AGENTS; RELEASE AGENTS; ENCAPSULATION OF ELECTRICAL DEVICES; CURING AGENT FOR EPOXIDES AEROJET GENERAL CORPORATION (US) 1997-06-10 US disclosed
WO-1996021657-A1 MONO-SUBSTITUTED FLUORINATED OXETANE MONOMERS AEROJET-GENERAL CORPORATION (US) 1996-07-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050154217-A1 Amorphous polyether glycols based on bis-substituted oxetane and tetrahydrofuran monomers GNE, PFAS, FTO EPHX1 1913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.