Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670928 | 0.88 | ALDH1A1 (0.65) | ALOX15ALDH1A1CYP1A2KDM4EMAPT | |
| Phenol SCHEMBL11597348 | 0.86 | ALDH1A1 (0.68) | ALOX15ALDH1A1CYP1A2KDM4EMAPT | |
| SCHEMBL2788258 | 0.80 | ALOX15 (0.58) | ALOX15ALDH1A1CYP1A2KDM4EMAPT | |
| SCHEMBL29808669 | 0.80 | ALOX15 (0.58) | ALOX15ALDH1A1CYP1A2KDM4EMAPT | |
| SCHEMBL11561364 | 0.78 | BCL2 (0.53) | ALOX15ALDH1A1CYP1A2KDM4EMAPT | |
| Hydroquinone SCHEMBL23089046 | 0.75 | ALDH1A1 (0.79) | ALOX15ALDH1A1CYP1A2KDM4EMAPT | |
| SCHEMBL11681090 | 0.74 | TYR (0.52) | ALOX15ALDH1A1CYP1A2KDM4EMAPT | |
| SCHEMBL11579753 | 0.74 | ALOX15 (0.47) | ALOX15ALDH1A1CYP1A2KDM4EMAPT | |
| SCHEMBL3628725 | 0.74 | ALOX15 (0.68) | ALOX15ALDH1A1CYP1A2KDM4EMAPT | |
| Phenol SCHEMBL27499906 | 0.74 | HSPA5 (0.61) | ALOX15ALDH1A1CYP1A2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1669376-B1 | Dual catalyst on a single support | NOVA CHEM INT SA (CH) | 2008-05-21 | — | — | EP | claimed |