SCHEMBL5089696

SCHEMBL5089696

Nc1ncnc2c1ncn2O[PH](=O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ENPP1 P22413 2/20 0.46
ENPP3 O14638 1/20 0.46
P2RY2 P41231 4/20 0.45
P2RX1 P51575 3/20 0.43
P2RX3 P56373 3/20 0.43
P2RX2 Q9UBL9 2/20 0.43
P2RY1 P47900 4/20 0.43
P2RY11 Q96G91 1/20 0.43
FGFR1 P11362 1/20 0.42
SLC22A6 Q4U2R8 1/20 0.42
P2RX4 Q99571 2/20 0.40
RNASEL Q05823 1/20 0.40
SRC P12931 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1071388 0.85 CDK1 (0.36) ENPP1ENPP3P2RY2P2RX1P2RX3
SCHEMBL1035726 0.82 ENPP1 (0.51) ENPP1ENPP3P2RY2P2RX1P2RX3
SCHEMBL2698569 0.82 ADORA2A (0.50)
SCHEMBL502621 0.81 ENPP1 (0.52) ENPP1ENPP3P2RY2P2RX1P2RX3
SCHEMBL8509835 0.81 ENPP1 (0.50) ENPP1ENPP3P2RY2P2RX1P2RX3
SCHEMBL9275960 0.77 PNP (0.55)
SCHEMBL27721221 0.77 FGFR1 (0.47) ENPP1ENPP3P2RY2P2RX1P2RX3
SCHEMBL283730 0.76 FGFR1 (0.51) ENPP1ENPP3P2RY2P2RY1P2RY11
SCHEMBL28296105 0.76 ADORA2A (0.47) FGFR1SLC22A6
Acetone SCHEMBL28162073 0.72 CYP3A4 (0.47) ENPP1P2RY2P2RY1P2RY11FGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11198904-B2 Substrate for medical test, gene sequencing method and gene sequencing chip BEIJING BOE OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2021-12-14 US disclosed
EP-3653693-A1 SUBSTRATE FOR USE IN MEDICAL TESTING, GENE SEQUENCING METHOD THEREOF, AND GENE SEQUENCING CHIP Boe Technology Group Co. Ltd. (CN) 2020-05-20 EP disclosed
US-20190345547-A1 SUBSTRATE FOR MEDICAL TEST, GENE SEQUENCING METHOD AND GENE SEQUENCING CHIP BEIJING BOE OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2019-11-14 US disclosed
US-20190256902-A1 GENE SEQUENCING CHIP, DEVICE AND METHOD BOE TECHNOLOGY GROUP CO., LTD. (CN) 2019-08-22 US disclosed
WO-2018194437-A2 NUCLEIC ACID MOLECULE TEMPLATE FOR DETECTING TARGET POINT MUTATION GENE AND GENETIC ANALYSIS METHOD USING SAME 이화여자대학교 산학협력단 2018-10-25 WO disclosed
US-20080241828-A1 DETECTION OF DNA METHYLATION USING RAMAN SPECTROSCOPY INTEL CORPORATION 2008-10-02 US disclosed
EP-0356130-A2 A mobile fl phage single-strand DNA origin of replication GENENCOR INTERNATIONAL, INC. (US) 1990-02-28 EP disclosed