Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB3 | Q16875 | 5/20 | 0.65 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.50 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 8/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 8/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | P4HB | P07237 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5090108 | 1.00 | PFKFB3 (0.65) | PFKFB3CYSLTR2CYSLTR1CYP1A1CYP1B1 | |
| SCHEMBL27665265 | 0.84 | PFKFB3 (0.56) | PFKFB3CYSLTR2CYSLTR1CYP1B1HDAC6 | |
| SCHEMBL5090157 | 0.81 | PFKFB3 (0.57) | PFKFB3CYP1A1CYP1B1HDAC6 | |
| SCHEMBL30209647 | 0.81 | PFKFB3 (0.55) | PFKFB3HDAC6BACE1 | |
| Pfk-158 SCHEMBL15287560 | 0.79 | PFKFB3 (1.00) | PFKFB3CYP1A1CYP1B1MAOBHDAC6 | |
| Pfk-158 SCHEMBL15287558 | 0.79 | PFKFB3 (1.00) | PFKFB3CYP1A1CYP1B1MAOBHDAC6 | |
| Pfk-158 SCHEMBL29534190 | 0.79 | PFKFB3 (1.00) | PFKFB3CYP1A1CYP1B1MAOBHDAC6 | |
| Pfk-158 SCHEMBL29538151 | 0.79 | PFKFB3 (1.00) | PFKFB3CYP1A1CYP1B1MAOBHDAC6 | |
| SCHEMBL5507715 | 0.78 | PFKFB3 (0.74) | PFKFB3CYSLTR2CYSLTR1HDAC6ALOX5 | |
| SCHEMBL10275157 | 0.78 | PFKFB3 (0.74) | PFKFB3CYSLTR2CYSLTR1HDAC6ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207608-A1 | 2-Propene-1-Ones As Hsp 70 Inducers | TORRENT PHARMACEUTICALS LTD. (IN) | 2008-08-28 | — | — | US | disclosed |
| EP-1748987-A2 | 2-PROPENE-1-ONES AS HSP 70 INDUCERS | Torrent Pharmaceuticals Ltd (IN) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005097746-A2 | 2-PROPENE-1-ONES AS HSP 70 INDUCERS | TORRENT PHARMACEUTICALS LTD (IN) | 2005-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207608-A1 | 2-Propene-1-Ones As Hsp 70 Inducers | HSPB1, HSF1, HSPE1 | PFKFB3 3216/4885CYSLTR2 1261/4885CYSLTR1 1328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.