SCHEMBL5090629

SCHEMBL5090629

CCCCCC1=Cc2ccccc2[C]1

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
KCNH2 Q12809 3/20 0.35
PTPN1 P18031 1/20 0.35
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33
CNR1 P21554 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CNR2 P34972 1/20 0.32
GPR84 Q9NQS5 1/20 0.32
HTR2A P28223 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5083726 0.98 LIPG (0.39) LIPGSIGMAR1KCNH2PTPN1NR1H2
SCHEMBL5090113 0.98 LIPG (0.39) LIPGSIGMAR1KCNH2PTPN1NR1H2
SCHEMBL5086386 0.95 SIGMAR1 (0.33) LIPGSIGMAR1
SCHEMBL5086961 0.87
SCHEMBL3685992 0.64 LIPG (0.43) LIPGSIGMAR1KCNH2PTPN1NR1H2
SCHEMBL10604576 0.64 PTPN1 (0.57) LIPGSIGMAR1KCNH2PTPN1NR1H2
SCHEMBL5085740 0.63 TSHR (0.35)
SCHEMBL3684071 0.63 LIPG (0.46) LIPGKCNH2PTPN1NR1H2NR1H3
SCHEMBL30037094 0.62 LIPG (0.65) LIPGKCNH2NR1H2NR1H3TDP1
SCHEMBL82794 0.62 LIPG (0.65) LIPGKCNH2NR1H2NR1H3TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1498178-B1 Transition metal complex and process for producing the same SUMITOMO CHEMICAL CO (JP) 2008-06-11 EP disclosed
EP-1498178-A2 Transition metal complex, process for producing the same, olefin polymerization catalyst containing the transition metal complex and process for producing olefin polymers Sumitomo Chemical Company, Limited (JP) 2005-01-19 EP disclosed
EP-0842939-B1 OLEFIN POLYMERIZATION CATALYST CONTAINING A TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING OLEFIN POLYMERS SUMITOMO CHEMICAL CO (JP) 2004-10-06 EP disclosed
US-6329478-B1 SOLUBILITY IN SATURATED HYDROCARBON SOLVENTS SUMITMO CHEMICAL COMPANY, LIMITED 2001-12-11 US disclosed
EP-0842939-A1 TRANSITION METAL COMPLEX, PROCESS FOR THE PREPARATION THEREOF, POLYMERIZATION CATALYST FOR OLEFINS CONTAINING THE COMPLEX, AND PROCESS FOR PRODUCING OLEFIN POLYMERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-05-20 EP disclosed