Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5087390 | 1.00 | FAAH (0.47) | FAAHCASP2DNM1NAAAHSP90AA1 | |
| SCHEMBL5138168 | 0.98 | FAAH (0.44) | FAAHCASP2DNM1NAAAHSP90AA1 | |
| SCHEMBL5087320 | 0.93 | FAAH (0.41) | FAAHCASP2DNM1NAAAHSP90AA1 | |
| SCHEMBL5138320 | 0.87 | FAAH (0.34) | FAAHCASP2DNM1NAAA | |
| SCHEMBL11132585 | 0.78 | CASP2 (0.74) | FAAHCASP2DNM1NAAAEPHX2 | |
| SCHEMBL20683710 | 0.78 | CASP2 (0.74) | FAAHCASP2DNM1NAAAEPHX2 | |
| SCHEMBL965531 | 0.78 | CASP2 (0.74) | FAAHCASP2DNM1NAAAEPHX2 | |
| SCHEMBL21548098 | 0.78 | CASP2 (0.74) | FAAHCASP2DNM1NAAAEPHX2 | |
| SCHEMBL29290542 | 0.78 | CASP2 (0.74) | FAAHCASP2DNM1NAAAEPHX2 | |
| SCHEMBL9230007 | 0.78 | CASP2 (0.74) | FAAHCASP2DNM1NAAAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968609-A2 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF HIGHLY LIPOPHILIC SULFHYDRYL COMPOUNDS | RND Pharmaceuticals, Inc. (US) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007073560-A2 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF HIGHLY LIPOPHILIC SULFHYDRYL COMPOUNDS | RND PHARMACEUTICALS, INC. (US) | 2007-06-28 | — | — | WO | disclosed |