SCHEMBL5092969

SCHEMBL5092969

c1c(-c2ccccc2)c(-c2ccccc2)c(-c2ccccc2)c(-c2ccccc2)c#1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46
HTT P42858 1/20 0.46
ALDH1A1 P00352 2/20 0.44
MAPK1 P28482 3/20 0.35
RAB9A P51151 2/20 0.35
NPC1 O15118 1/20 0.35
ACHE P22303 1/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
BRD4 O60885 2/20 0.33
CHEK1 O14757 1/20 0.33
AKT2 P31751 1/20 0.33
BRD2 P25440 1/20 0.33
POLB P06746 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA2B P29275 1/20 0.33
ADORA1 P30542 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL340073 0.82 LMNA (0.46) LMNAMAPTHTTALDH1A1MAPK1
SCHEMBL619469 0.80 MAPT (0.43) LMNAMAPTHTTALDH1A1MAPK1
SCHEMBL339066 0.76 LMNA (0.40) LMNAMAPTHTTALDH1A1MAPK1
SCHEMBL216526 0.73 ALDH1A1 (0.67) LMNAMAPTHTTALDH1A1MAPK1
SCHEMBL617580 0.71 ALDH1A1 (0.53) LMNAMAPTHTTALDH1A1MAPK1
SCHEMBL5637259 0.70 ALDH1A1 (0.61) LMNAMAPTHTTALDH1A1MAPK1
SCHEMBL21248606 0.69 MAPT (0.39) LMNAMAPTHTTALDH1A1MAPK1
SCHEMBL5949483 0.67 ALDH1A1 (0.69) LMNAMAPTHTTALDH1A1MAPK1
SCHEMBL13319607 0.67 ALDH1A1 (0.50) LMNAMAPTHTTALDH1A1MAPK1
SCHEMBL4855476 0.67 ALDH1A1 (0.47) LMNAMAPTHTTALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9865816-B2 Solution for forming function layer contained in organic light emitting element and method for manufacturing organic light emitting element JOLED INC. (JP) 2018-01-09 US disclosed
US-20170117471-A1 SOLUTION FOR FORMING FUNCTION LAYER CONTAINED IN ORGANIC LIGHT EMITTING ELEMENT AND METHOD FOR MANUFACTURING ORGANIC LIGHT EMITTING ELEMENT MAGNOLIA BLUE CORPORATION (JP) 2017-04-27 US disclosed
US-20080315185-A1 Photodetector FUJIFILM CORPORATION (JP) 2008-12-25 US disclosed