Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5091596 | 1.00 | FDPS (0.44) | FDPSDNM1OPRM1SPHK1LMNA | |
| Bromide SCHEMBL2517543 | 1.00 | FDPS (0.44) | FDPSDNM1OPRM1SPHK1LMNA | |
| Bromide SCHEMBL5085195 | 1.00 | FDPS (0.44) | FDPSDNM1OPRM1SPHK1LMNA | |
| Bromide SCHEMBL5089308 | 1.00 | FDPS (0.44) | FDPSDNM1OPRM1SPHK1LMNA | |
| Bromide SCHEMBL5088631 | 1.00 | FDPS (0.44) | FDPSDNM1OPRM1SPHK1LMNA | |
| Bromide SCHEMBL5138211 | 1.00 | FDPS (0.44) | FDPSDNM1OPRM1SPHK1LMNA | |
| Bromide SCHEMBL5087215 | 1.00 | FDPS (0.44) | FDPSDNM1OPRM1SPHK1LMNA | |
| SCHEMBL16390875 | 0.98 | FDPS (0.46) | FDPSDNM1OPRM1SPHK1LMNA | |
| SCHEMBL2406522 | 0.98 | FDPS (0.46) | FDPSDNM1OPRM1SPHK1LMNA | |
| SCHEMBL16465044 | 0.98 | FDPS (0.46) | FDPSDNM1OPRM1SPHK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10547019-B2 | Electrochemical luminescent cell and composition for forming luminescent layer of electrochemical luminescent cell | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2020-01-28 | — | — | US | disclosed |
| EP-3103156-B1 | GELATED IONIC LIQUID FILM-COATED SURFACES AND USES THEREOF | GELION TECH PTY LTD (AU) | 2019-06-12 | — | — | EP | disclosed |
| US-20190097273-A1 | GELATED IONIC LIQUID FILM-COATED SURFACES AND USES THEREOF | GELION TECH PTY LTD (AU) | 2019-03-28 | — | — | US | disclosed |
| EP-3205924-B1 | ELECTROCHEMICAL LUMINESCENT CELL AND COMPOSITION FOR FORMING LUMINESCENT LAYER OF ELECTROCHEMICAL LUMINESCENT CELL | NIPPON CHEMICAL IND (JP) | 2018-11-28 | — | — | EP | disclosed |
| US-10122049-B2 | Gelated ionic liquid film-coated surfaces and uses thereof | GELION TECHNOLOGIES PTY LTD (AU) | 2018-11-06 | — | — | US | disclosed |
| US-20170294616-A1 | ELECTROCHEMICAL LUMINESCENT CELL AND COMPOSITION FOR FORMING LUMINESCENT LAYER OF ELECTROCHEMICAL LUMINESCENT CELL | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2017-10-12 | — | — | US | disclosed |
| EP-3205924-A1 | ELECTROCHEMICAL LUMINESCENT CELL AND COMPOSITION FOR FORMING LUMINESCENT LAYER OF ELECTROCHEMICAL LUMINESCENT CELL | Nippon Chemical Industrial Co., Ltd. (JP) | 2017-08-16 | — | — | EP | disclosed |
| EP-3103156-A1 | GELATED IONIC LIQUID FILM-COATED SURFACES AND USES THEREOF | Gelion Technologies PTY LTD (AU) | 2016-12-14 | — | — | EP | disclosed |
| US-20160351969-A1 | GELATED IONIC LIQUID FILM-COATED SURFACES AND USES THEREOF | GELION TECHNOLOGIES PTY LTD (AU) | 2016-12-01 | — | — | US | disclosed |
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |