Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5091596 | 1.00 | FDPS (0.44) | FDPSDNM1OPRM1SPHK1LMNA | |
| Bromide SCHEMBL5085195 | 1.00 | FDPS (0.44) | FDPSDNM1OPRM1SPHK1LMNA | |
| Bromide SCHEMBL5093153 | 1.00 | FDPS (0.44) | FDPSDNM1OPRM1SPHK1LMNA | |
| Bromide SCHEMBL5089308 | 1.00 | FDPS (0.44) | FDPSDNM1OPRM1SPHK1LMNA | |
| Bromide SCHEMBL5088631 | 1.00 | FDPS (0.44) | FDPSDNM1OPRM1SPHK1LMNA | |
| Bromide SCHEMBL5138211 | 1.00 | FDPS (0.44) | FDPSDNM1OPRM1SPHK1LMNA | |
| Bromide SCHEMBL5087215 | 1.00 | FDPS (0.44) | FDPSDNM1OPRM1SPHK1LMNA | |
| SCHEMBL16390875 | 0.98 | FDPS (0.46) | FDPSDNM1OPRM1SPHK1LMNA | |
| SCHEMBL2406522 | 0.98 | FDPS (0.46) | FDPSDNM1OPRM1SPHK1LMNA | |
| SCHEMBL16465044 | 0.98 | FDPS (0.46) | FDPSDNM1OPRM1SPHK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605223-A | Method for preparing 2,4, 5-trifluorobenzyl bromide by using 2,4, 5-trifluorobenzyl chloride | 浙江永太科技股份有限公司 | 2022-06-10 | — | — | CN | claimed |
| CN-112795998-B | Preparation method of non-intrinsic flame-retardant high-strength polyester industrial yarn | 湖南美莱珀科技发展有限公司 | 2022-05-31 | — | — | CN | claimed |
| CN-112812285-B | Macromolecular flame retardant and preparation method and application thereof | 湖南美莱珀科技发展有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-112812285-A | Macromolecular flame retardant and preparation method and application thereof | 湖南美莱珀科技发展有限公司 | 2021-05-18 | — | — | CN | claimed |
| CN-112795998-A | Preparation method of non-intrinsic flame-retardant high-strength polyester industrial yarn | 湖南美莱珀科技发展有限公司 | 2021-05-14 | — | — | CN | claimed |
| US-8430169-B2 | Method for managing hydrates in subsea production line | EXXONMOBIL UPSTREAM RESEARCH COMPANY (US) | 2013-04-30 | — | — | US | claimed |
| US-20100193194-A1 | Method For Managing Hydrates In Subsea Production Line | STOISITS RICHARD F | 2010-08-05 | — | — | US | claimed |
| WO-2009042319-A1 | METHOD FOR MANAGING HYDRATES IN SUBSEA PRODUCTION LINE | EXXONMOBIL UPSTREAM RESEARCH COMPANY (US) | 2009-04-02 | — | — | WO | claimed |
| WO-2025121285-A1 | PHOSPHINE-PALLADIUM COMPLEX, POLYMERIZATION CATALYST, AND METHOD FOR PRODUCING AROMATIC POLYMER | 日本化学工業株式会社 | 2025-06-12 | — | — | WO | disclosed |
| US-20250122418-A1 | Synergistic Blends Of Anti-Agglomerant Gas Hydrate Inhibitors With Quaternary Alkyl Ammonium Compounds | CLARIANT INT LTD (CH) | 2025-04-17 | — | — | US | disclosed |
| US-12129427-B2 | Synergistic blends of anti-agglomerant gas hydrate inhibitors with quaternary alkyl ammonium compounds | CLARIANT INTERNATIONAL LTD (CH) | 2024-10-29 | — | — | US | disclosed |
| US-20240318064-A1 | Method Of And A Composition For Controlling Gas Hydrate Blockage Through The Addition Of A Synergistically Acting Blend With Alkoxylates Of Fatty Alcohols, Fatty Amines And Fatty Acids | CLARIANT INTERNATIONAL LTD (CH) | 2024-09-26 | — | — | US | disclosed |
| US-12037537-B2 | Method of and a composition for controlling gas hydrate blockage through the addition of a synergistically acting blend with alkoxylates of fatty alcohols, fatty amines and fatty acids | CLARIANT INTERNATIONAL LTD (CH) | 2024-07-16 | — | — | US | disclosed |
| CN-114605223-B | Method for preparing 2,4, 5-trifluoro-benzyl bromide by using 2,4, 5-trifluoro-benzyl chloride | 浙江永太科技股份有限公司 | 2024-03-15 | — | — | CN | disclosed |
| US-20050085675-A1 | Methods for inhibiting hydrate blockage in oil and gas pipelines using ester compounds | CHAMPION TECHNOLOGIES, INC. | 2005-04-21 | — | — | US | disclosed |
| US-20050081714-A1 | Methods for inhibiting hydrate blockage in oil and gas pipelines using simple quaternary ammonium and phosphonium compounds | HARBISON-FISCHER, INC. | 2005-04-21 | — | — | US | disclosed |
| US-20050085676-A1 | Methods for inhibiting hydrate blockage in oil and gas pipelines using betaines and amine oxides | CHAMPION TECHNOLOGIES, INC. | 2005-04-21 | — | — | US | disclosed |
| US-4522950-A | 2,3-Dihydrofurans useful as fungicides | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1985-06-11 | — | — | US | disclosed |
| US-4234488-A | FLUORESCENT DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-11-18 | — | — | US | disclosed |
| US-4147865-A | Benz-(C,D)-indolyl compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12129427-B2 | Synergistic blends of anti-agglomerant gas hydrate inhibitors with quaternary alkyl ammonium compounds | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, RCC1, MTDH | FDPS 4777/4885DNM1 703/4885OPRM1 310/4885 |
| US-20240318064-A1 | Method Of And A Composition For Controlling Gas Hydrate Blockage Through The Addition Of A Synergistically Acting Blend With Alkoxylates Of Fatty Alcohols, Fatty Amines And Fatty Acids | FFAR2, FFAR3, FAAH2 | FDPS 3107/4885DNM1 1467/4885OPRM1 218/4885 |
| US-20250122418-A1 | Synergistic Blends Of Anti-Agglomerant Gas Hydrate Inhibitors With Quaternary Alkyl Ammonium Compounds | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HDHD5, AQP1 | FDPS 4279/4885DNM1 663/4885OPRM1 1767/4885 |
| US-12037537-B2 | Method of and a composition for controlling gas hydrate blockage through the addition of a synergistically acting blend with alkoxylates of fatty alcohols, fatty amines and fatty acids | FAAH2, FAAH, FFAR2 | FDPS 2353/4885DNM1 1195/4885OPRM1 410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.