Azobenzene

Azobenzene

SCHEMBL509328

C=CC(=O)O.c1ccc(/N=N/c2ccccc2)cc1

nearest known ligand 0.57

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.57
TRPA1 O75762 1/20 0.56
MEN1 O00255 6/20 0.50
KMT2A Q03164 6/20 0.50
NPC1 O15118 2/20 0.50
AKT1 P31749 1/20 0.48
LMNA P02545 2/20 0.48
MAPT P10636 7/20 0.47
RAB9A P51151 3/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
KDM4E B2RXH2 2/20 0.47
MAPK1 P28482 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
HSP90AA1 P07900 1/20 0.47
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Azobenzene SCHEMBL27865838 1.00 ALDH1A1 (0.57) ALDH1A1TRPA1MEN1KMT2ANPC1
Azobenzene SCHEMBL30414107 1.00 ALDH1A1 (0.57) ALDH1A1TRPA1MEN1KMT2ANPC1
Azobenzene SCHEMBL29087973 0.94 ALDH1A1 (0.50) ALDH1A1TRPA1MEN1KMT2ANPC1
Azobenzene SCHEMBL28297043 0.86 ALDH1A1 (0.52) ALDH1A1TRPA1MEN1KMT2ANPC1
Azobenzene SCHEMBL28946018 0.86 ALDH1A1 (0.52) ALDH1A1TRPA1MEN1KMT2ANPC1
Azobenzene SCHEMBL19813944 0.86 ALDH1A1 (0.52) ALDH1A1TRPA1MEN1KMT2ANPC1
Azobenzene SCHEMBL29264423 0.85 ALDH1A1 (0.50) ALDH1A1TRPA1MEN1KMT2ANPC1
Acrylic Acid SCHEMBL28477546 0.84 TRPA1 (0.42) ALDH1A1TRPA1MEN1KMT2ANPC1
Azobenzene SCHEMBL28208079 0.84 MAPT (0.43) ALDH1A1TRPA1MEN1KMT2ANPC1
Azobenzene SCHEMBL28208076 0.84 MAPT (0.43) ALDH1A1TRPA1MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8435333-B2 Photo-switchable membrane and method UNIVERSITY OF ROCHESTER (US) 2013-05-07 US disclosed
US-20120025136-A1 PHOTO-SWITCHABLE MEMBRANE AND METHOD UNIVERSITY OF ROCHESTER (US) 2012-02-02 US disclosed