SCHEMBL509444

SCHEMBL509444

CC(=O)O[Si](OC(C)=O)(OC(C)=O)C(C)C

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
ALDH1A1 P00352 2/20 0.35
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM1 P11229 1/20 0.31
TBXA2R P21731 1/20 0.31
GALR3 O60755 1/20 0.30
MAPT P10636 1/20 0.30
BLM P54132 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6267833 0.82 TSHR (0.41) TSHRALDH1A1CHRM2CHRM4CHRM1
SCHEMBL11446500 0.78 TSHR (0.38) TSHRALDH1A1
SCHEMBL6390819 0.78 TSHR (0.38) TSHRALDH1A1
SCHEMBL475861 0.77 TSHR (0.41) TSHRALDH1A1CHRM2CHRM4CHRM1
SCHEMBL707326 0.77 TSHR (0.41) TSHRALDH1A1CHRM2CHRM4CHRM1
SCHEMBL31015810 0.76 TSHR (0.46) TSHRALDH1A1
SCHEMBL11851987 0.76 TSHR (0.48) TSHRALDH1A1CHRM2CHRM4CHRM1
SCHEMBL476054 0.74 TSHR (0.39) TSHRALDH1A1CHRM2CHRM4CHRM1
SCHEMBL3214845 0.74 TSHR (0.35) TSHRALDH1A1CHRM2CHRM4CHRM1
SCHEMBL28912248 0.72 TSHR (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110964218-B Water-resistant PVA film and preparation method thereof 江门市新构思环保科技有限公司 2022-03-11 CN claimed
CN-111909519-A Flexible heat-conducting silicon rubber and preparation method and application thereof 深圳市新亚新材料有限公司 2020-11-10 CN claimed
CN-110964218-A Water-resistant PVA film and preparation method thereof 江门市江海区依科希环保科技有限公司 2020-04-07 CN claimed
US-8716417-B2 Olefin polymerization catalyst and preparation method and use thereof PETROCHINA COMPANY LIMITED (CN) 2014-05-06 US claimed
US-4207424-A ALUMINA PRETREATED WITH SILYLATING AGENT AT ELEVATED TEMPERAUTRE HALCON RESEARCH & DEVELOPMENT CORPORATION (US) 1980-06-10 US claimed
CN-110964218-B Water-resistant PVA film and preparation method thereof 江门市新构思环保科技有限公司 2022-03-11 CN disclosed
CN-110603283-B Hydrosilylation curable silicone resins 美国陶氏有机硅公司 2022-02-11 CN disclosed
EP-3635033-B1 HYDROSILYLATION CURABLE SILICONE RESIN DOW SILICONES CORP (US) 2021-02-24 EP disclosed
CN-109852339-B Fluorosilicone rubber composition, method for producing the same, and sealant and coating prepared from the same 深圳市冠恒新材料科技有限公司 2021-01-15 CN disclosed
CN-108291030-B Methods and compositions for hydrosilylation of alkyl carboxylates and hydrogen-terminated organosiloxane oligomers using iridium complex catalysts 美国陶氏有机硅公司 2021-01-05 CN disclosed
CN-111909519-A Flexible heat-conducting silicon rubber and preparation method and application thereof 深圳市新亚新材料有限公司 2020-11-10 CN disclosed
US-10793681-B1 Hydrosilylation curable silicone resin DOW SILICONES CORPORATION (US) 2020-10-06 US disclosed
US-4207424-A ALUMINA PRETREATED WITH SILYLATING AGENT AT ELEVATED TEMPERAUTRE HALCON RESEARCH & DEVELOPMENT CORPORATION (US) 1980-06-10 US disclosed
US-4152343-A REACTING AN ORGANIC SILICATE OR SILANETRIOL DERIVATIVE WITH A DIALKYLTIN CAROXYLIC ACID SALT WACKER-CHEMIE GMBH (DE) 1979-05-01 US disclosed
US-4137249-A Silicon-tin compounds WACKER-CHEMIE GMBH (DE) 1979-01-30 US disclosed
US-4123472-A POLYMERIZING ACRYLIC ESTERS AND NITRILES IN THE PRESENCE OF ORGANOPOLYSILOXANES AND FREE RADICAL CATALYST, CROSSLINKING SWS SILICONES CORPORATION (US) 1978-10-31 US disclosed
US-4102860-A ROOM TEMPERATURE CURING WACKER-CHEMIE GMBH (DE) 1978-07-25 US disclosed
US-4045602-A ADHESION OF ORGANOPOLYSILOXANE ELASTOMERS TO SUBSTRATES WACKER-CHEMIE GMBH (DT) 1977-08-30 US disclosed
US-4032499-A GRAFT POLYMERIZATION USING FREE RADICAL CATALYST, NONSOLVENT CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DT) 1977-06-28 US disclosed
US-4026853-A Curable bituminous organopolysiloxane compositions CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DT) 1977-05-31 US disclosed