Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL2354846 | 1.00 | TSHR (0.50) | TSHRTDP1TP53ALDH1A1LMNA | |
| Methylene Chloride SCHEMBL1728893 | 1.00 | TSHR (0.50) | TSHRTDP1TP53ALDH1A1LMNA | |
| Methylene Chloride SCHEMBL4920513 | 1.00 | TSHR (0.50) | TSHRTDP1TP53ALDH1A1LMNA | |
| Methylene Chloride SCHEMBL7537653 | 1.00 | TSHR (0.50) | TSHRTDP1TP53ALDH1A1LMNA | |
| Methylene Chloride SCHEMBL5679533 | 1.00 | TSHR (0.50) | TSHRTDP1TP53ALDH1A1LMNA | |
| Methylene Chloride SCHEMBL703430 | 1.00 | TSHR (0.50) | TSHRTDP1TP53ALDH1A1LMNA | |
| Methylene Chloride SCHEMBL723498 | 1.00 | TSHR (0.50) | TSHRTDP1TP53ALDH1A1LMNA | |
| Methylene Chloride SCHEMBL2392102 | 1.00 | TSHR (0.50) | TSHRTDP1TP53ALDH1A1LMNA | |
| Methylene Chloride SCHEMBL37333 | 1.00 | — | — | |
| Methylene Chloride SCHEMBL2350111 | 1.00 | TSHR (0.50) | TSHRTDP1TP53ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115286595-A | Preparation method of hydrobromic acid vortioxetine impurity | 福建省福抗药业股份有限公司 | 2022-11-04 | — | — | CN | claimed |
| CN-112979618-A | Indirubin derivative and preparation method and application thereof | 东南大学 | 2021-06-18 | — | — | CN | claimed |
| CN-118307534-A | LTA4H inhibitors and uses thereof | 上海海雁医药科技有限公司 | 2024-07-09 | — | — | CN | disclosed |
| WO-2024140990-A1 | PYRAZOLE FUSED RING COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2024-07-04 | — | — | WO | disclosed |
| WO-2024140595-A1 | TRICYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 珂阑(上海)医药科技有限公司 | 2024-07-04 | — | — | WO | disclosed |
| CN-118255685-A | Tricyclic compound, pharmaceutical composition and application thereof | 珂阑(上海)医药科技有限公司 | 2024-06-28 | — | — | CN | disclosed |
| EP-4387966-A1 | PYRIDAZINONE OR PYRIDINONE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2024-06-26 | — | — | EP | disclosed |
| CN-118184669-A | Macrocyclic compounds as multi-target kinase inhibitors | 北京伯汇生物技术有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-118164893-A | Pentamethine cyanine dye, synthesis and application | 中国科学院大连化学物理研究所 | 2024-06-11 | — | — | CN | disclosed |
| CN-118055929-A | 2, 6-Piperidinedione compound and application thereof | 南京明德新药研发有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-111989321-B | KRAS G12C inhibitors | 米拉蒂治疗股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| WO-1997022604-A1 | NOVEL SUBSTITUTED 4-(1H-BENZIMIDAZOL-2-YL)[1,4]DIAZEPANES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | HOECHST MARION ROUSSEL, INC. (US) | 1997-06-26 | — | — | WO | disclosed |
| WO-1997019074-A1 | SUBSTITUTED 4-(1H-BENZIMIDAZOL-2-YL-AMINO)PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | HOECHST MARION ROUSSEL, INC. (US) | 1997-05-29 | — | — | WO | disclosed |
| EP-0678097-A1 | NOVEL COLON- OR ILEUM-SPECIFIC STEROID DERIVATIVES | AKTIEBOLAGET ASTRA (SE) | 1995-10-25 | — | — | EP | disclosed |
| US-5457091-A | N1-substituted 1H-1,2,3-triazolo[4,5,-D]pyrimidines, a process for their preparation and their use as antiviral agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-10 | — | — | US | disclosed |
| US-5440046-A | Angiotensin antagonist, hypotensive agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-08 | — | — | US | disclosed |
| US-5350751-A | Hypotensive agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-09-27 | — | — | US | disclosed |
| WO-1994015947-A1 | NOVEL COLON- OR ILEUM-SPECIFIC STEROID DERIVATIVES | ASTRA AKTIEBOLAG (SE) | 1994-07-21 | — | — | WO | disclosed |
| EP-0146866-B1 | PHENYLSULFONEPHTHALEINYL-BETA-D-GALACTOSIDES, METHODS FOR THEIR PREPARATION AND THEIR USE IN THE DETERMINATION OF BETA-D-GALACTOSIDASE | Roche Diagnostics GmbH (DE) | 1991-06-19 | — | — | EP | disclosed |
| EP-0146866-A2 | Phenylsulfonephthaleinyl-beta-D-galactosides, methods for their preparation and their use in the determination of beta-D-galactosidase | Roche Diagnostics GmbH (DE) | 1985-07-03 | — | — | EP | disclosed |