Methylene Chloride

Methylene Chloride

SCHEMBL703430

ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.OCC(Cl)Cl

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
TP53 P04637 1/20 0.50
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylene Chloride SCHEMBL2354846 1.00 TSHR (0.50) TSHRTDP1TP53ALDH1A1LMNA
Methylene Chloride SCHEMBL1728893 1.00 TSHR (0.50) TSHRTDP1TP53ALDH1A1LMNA
Methylene Chloride SCHEMBL4920513 1.00 TSHR (0.50) TSHRTDP1TP53ALDH1A1LMNA
Methylene Chloride SCHEMBL7537653 1.00 TSHR (0.50) TSHRTDP1TP53ALDH1A1LMNA
Methylene Chloride SCHEMBL5679533 1.00 TSHR (0.50) TSHRTDP1TP53ALDH1A1LMNA
Methylene Chloride SCHEMBL509509 1.00 TSHR (0.50) TSHRTDP1TP53ALDH1A1LMNA
Methylene Chloride SCHEMBL723498 1.00 TSHR (0.50) TSHRTDP1TP53ALDH1A1LMNA
Methylene Chloride SCHEMBL2392102 1.00 TSHR (0.50) TSHRTDP1TP53ALDH1A1LMNA
Methylene Chloride SCHEMBL37333 1.00
Methylene Chloride SCHEMBL2350111 1.00 TSHR (0.50) TSHRTDP1TP53ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118307969-A Meta-aryl ketone substituted heptamethine cyanine dye and synthetic method and application thereof 大连理工大学 2024-07-09 CN disclosed
WO-2024140990-A1 PYRAZOLE FUSED RING COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 江苏亚虹医药科技股份有限公司 2024-07-04 WO disclosed
EP-3608312-B1 SUBSTITUTED IMIDAZOLE SALT COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF XIAMEN VIVOHEALTHS TECH CO LTD (CN) 2024-06-26 EP disclosed
WO-2024125627-A1 CAMPTOTHECIN COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海齐鲁制药研究中心有限公司 2024-06-20 WO disclosed
EP-3345900-B1 2, 4-DI-(NITROGEN CONTAINING GROUP) SUBSTITUTED PYRIMIDINE COMPOUND AND PREPARATION METHOD AND USE THEREOF BEBETTER MED INC (CN) 2024-06-12 EP disclosed
EP-4375282-A1 PREPARATION METHOD FOR HEPATITIS B VIRUS NUCLEOCAPSID INHIBITOR Shanghai Zhimeng Biopharma, Inc. (CN) 2024-05-29 EP disclosed
CN-118084864-A PRMT4 inhibitor, and pharmaceutical composition, pharmaceutical preparation and application thereof 北京福元医药股份有限公司 2024-05-28 CN disclosed
CN-118076612-A Sulfur-containing heteroaromatic tricyclic KRAS inhibitors 医睿世康药业研发公司 2024-05-24 CN disclosed
CN-117917398-A Ionizable lipid compound, nucleic acid drug molecule delivery system and application 华中师范大学 2024-04-23 CN disclosed
CN-116888108-B Novel EGFR degradation agent 上海齐鲁制药研究中心有限公司 2024-04-19 CN disclosed
US-5541198-A ANTISTICKING AGENTS FOR PLATELETS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1996-07-30 US disclosed
EP-0651747-B1 CARBOSTYRYL DERIVATIVES OTSUKA PHARMA CO LTD (JP) 1996-03-27 EP disclosed
US-5470833-A Vasodilators, bronchodilators BANYU PHARMACEUTICAL CO., LTD. (JP) 1995-11-28 US disclosed
US-5444152-A Vasolidator or bronchodilator BANYU PHARMACEUTICAL CO., LTD. (JP) 1995-08-22 US disclosed
EP-0651747-A1 CARBOSTYRIL DERIVATIVES. OTSUKA PHARMA CO LTD (JP) 1995-05-10 EP disclosed
WO-1994026732-A1 CARBOSTYRIL DERIVATIVES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-11-24 WO disclosed
US-5238938-A Nephrosis OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-08-24 US disclosed
EP-0460679-A2 Endothelin antagonistic peptide derivatives Banyu Pharmaceutical Co., Ltd. (JP) 1991-12-11 EP disclosed
EP-0411150-A1 INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-02-06 EP disclosed
US-4540776-A Reactive fluorotriazinylaminonaphthotriazolyphenylazopyridone or pyrimidone dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1985-09-10 US disclosed