Methylene Chloride

Methylene Chloride

SCHEMBL7537653

ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.ClCCl.OCC(Cl)Cl

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
TP53 P04637 1/20 0.50
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylene Chloride SCHEMBL2354846 1.00 TSHR (0.50) TSHRTDP1TP53ALDH1A1LMNA
Methylene Chloride SCHEMBL1728893 1.00 TSHR (0.50) TSHRTDP1TP53ALDH1A1LMNA
Methylene Chloride SCHEMBL4920513 1.00 TSHR (0.50) TSHRTDP1TP53ALDH1A1LMNA
Methylene Chloride SCHEMBL5679533 1.00 TSHR (0.50) TSHRTDP1TP53ALDH1A1LMNA
Methylene Chloride SCHEMBL703430 1.00 TSHR (0.50) TSHRTDP1TP53ALDH1A1LMNA
Methylene Chloride SCHEMBL509509 1.00 TSHR (0.50) TSHRTDP1TP53ALDH1A1LMNA
Methylene Chloride SCHEMBL723498 1.00 TSHR (0.50) TSHRTDP1TP53ALDH1A1LMNA
Methylene Chloride SCHEMBL2392102 1.00 TSHR (0.50) TSHRTDP1TP53ALDH1A1LMNA
Methylene Chloride SCHEMBL37333 1.00
Methylene Chloride SCHEMBL2350111 1.00 TSHR (0.50) TSHRTDP1TP53ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113788783-B Self-reporting photosensitizer and preparation method and application thereof 江南大学 2023-08-22 CN disclosed
CN-113788783-A Self-reporting photosensitizer and preparation method and application thereof 江南大学 2021-12-14 CN disclosed
EP-0650476-B1 PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS OTSUKA PHARMA CO LTD (JP) 2002-06-26 EP disclosed
US-6136826-A AMINOPIPERIDINE COMPOUNDS SUBSTITUTED WITH ALKANOYL OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2000-10-24 US disclosed
US-5760058-A Peripheral vasodilating agent containing piperidine derivative as active ingredient OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1998-06-02 US disclosed
EP-0650476-A1 PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-05-03 EP disclosed
WO-1994022826-A1 PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-10-13 WO disclosed