Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 13/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MARS1 | P56192 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5705016 | 0.87 | SRD5A2 (0.69) | SRD5A2CNR1KDM4ENPC1CRHBP | |
| SCHEMBL23484573 | 0.86 | SRD5A2 (0.58) | SRD5A2CNR1KDM4ENPC1CRHBP | |
| SCHEMBL4300785 | 0.86 | SRD5A2 (0.68) | SRD5A2CNR1KDM4ENPC1CRHBP | |
| SCHEMBL5089941 | 0.82 | SRD5A2 (0.51) | SRD5A2CNR1KDM4ENPC1RAB9A | |
| SCHEMBL9812955 | 0.79 | SRD5A2 (0.53) | SRD5A2KDM4ENPC1CRHBPRAB9A | |
| SCHEMBL9812968 | 0.78 | TSHR (0.46) | SRD5A2KDM4ENPC1RAB9A | |
| SCHEMBL444367 | 0.76 | SRD5A2 (0.90) | SRD5A2KDM4ENPC1CRHBPRAB9A | |
| SCHEMBL5093177 | 0.75 | CNR1 (0.74) | CNR1CNR2 | |
| SCHEMBL30837198 | 0.75 | SRD5A2 (0.66) | SRD5A2CNR1KDM4ENPC1CRHBP | |
| SCHEMBL16492515 | 0.75 | SRD5A2 (0.66) | SRD5A2CNR1KDM4ENPC1CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7390924-B2 | Terphenyl derivatives, preparation thereof, compositions containing same | SANOFI-AVENTIS (FR) | 2008-06-24 | — | — | US | disclosed |
| US-20060167049-A1 | Terphenly derivatives, preparation thereof, compositions containing same | SANOFI-AVENTIS (FR) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167049-A1 | Terphenly derivatives, preparation thereof, compositions containing same | CNR1, CNR2, TRPV1 | SRD5A2 1598/4885CNR1 1/4885KDM4E 1359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.