Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MARS1 | P56192 | 2/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.48 |
| ▸ | CDH1 | P12830 | 1/20 | 0.48 |
| ▸ | APC | P25054 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5095111 | 0.87 | SRD5A2 (0.56) | SRD5A2KDM4ENPC1CRHBPRAB9A | |
| SCHEMBL23484575 | 0.86 | SRD5A2 (0.73) | SRD5A2KDM4ENPC1CRHBPRAB9A | |
| SCHEMBL444367 | 0.86 | SRD5A2 (0.90) | SRD5A2KDM4ENPC1CRHBPRAB9A | |
| SCHEMBL5089941 | 0.82 | SRD5A2 (0.51) | SRD5A2KDM4ENPC1RAB9ACNR1 | |
| SCHEMBL5355700 | 0.81 | CNR1 (0.67) | SRD5A2KDM4ENPC1CRHBPRAB9A | |
| SCHEMBL2743754 | 0.81 | SRD5A2 (0.56) | SRD5A2KDM4ENPC1CRHBPRAB9A | |
| SCHEMBL5937383 | 0.80 | SRD5A2 (0.58) | SRD5A2KDM4ESRD5A1TSHRALOX15 | |
| SCHEMBL6253145 | 0.79 | SRD5A2 (0.72) | SRD5A2KDM4ENPC1CRHBPRAB9A | |
| SCHEMBL2769863 | 0.78 | TSHR (0.71) | SRD5A2KDM4ESRD5A1TSHRALOX15 | |
| SCHEMBL14273027 | 0.78 | TSHR (0.55) | SRD5A2KDM4ESRD5A1TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497274-B1 | TERPHENYL DERIVATIVES, PREPARATION THEREOF, COMPOSITIONS CONTAINING SAME | SANOFI AVENTIS (FR) | 2006-09-13 | — | — | EP | disclosed |