Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 5/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23484572 | 0.88 | SLC6A3 (0.54) | SRD5A2CNR1PTGS2SLC6A3SLC6A4 | |
| SCHEMBL4300304 | 0.88 | SRD5A2 (0.60) | SRD5A2CNR1SLC6A3SLC6A4ALPL | |
| SCHEMBL5359287 | 0.83 | CNR1 (0.62) | CNR1ALPL | |
| SCHEMBL5705016 | 0.82 | SRD5A2 (0.69) | SRD5A2CNR1NPC1RAB9AKDM4E | |
| SCHEMBL5095111 | 0.82 | SRD5A2 (0.56) | SRD5A2CNR1NPC1RAB9AKDM4E | |
| SCHEMBL13960241 | 0.81 | MAPT (0.56) | SLC6A3ALPLMAPTFLT1FLT4 | |
| SCHEMBL4710854 | 0.81 | SLC2A1 (0.54) | PTGS2SLC6A3SLC6A4MAPTMAP2K4 | |
| SCHEMBL26573424 | 0.81 | SLC6A4 (0.65) | PTGS2SLC6A3SLC6A4MAPTMAPK14 | |
| SCHEMBL2721892 | 0.79 | MAPT (0.57) | PTGS2SLC6A3SLC6A4MAPTMAPK14 | |
| SCHEMBL6252933 | 0.78 | SRD5A2 (0.59) | SRD5A2PTGS2EGFRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7390924-B2 | Terphenyl derivatives, preparation thereof, compositions containing same | SANOFI-AVENTIS (FR) | 2008-06-24 | — | — | US | disclosed |
| US-20060167049-A1 | Terphenly derivatives, preparation thereof, compositions containing same | SANOFI-AVENTIS (FR) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167049-A1 | Terphenly derivatives, preparation thereof, compositions containing same | CNR1, CNR2, TRPV1 | SRD5A2 1598/4885CNR1 1/4885PTGS2 1413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.