SCHEMBL50954

SCHEMBL50954

CC(c1ccccc1)C1CO1

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 4/20 0.47
CHRM4 P08173 4/20 0.47
CHRM5 P08912 4/20 0.47
CHRM1 P11229 4/20 0.47
CHRM3 P20309 4/20 0.47
APOBEC3A P31941 1/20 0.41
KMT2A Q03164 1/20 0.41
CTDSP1 Q9GZU7 1/20 0.41
APOBEC3G Q9HC16 1/20 0.41
CYP2D6 P10635 1/20 0.40
TSHR P16473 1/20 0.39
DPP4 P27487 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14539691 1.00 CHRM2 (0.47) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL16259362 1.00 CHRM2 (0.47) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL16259363 1.00 CHRM2 (0.47) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL247653 0.81 CHRM2 (0.59) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL244373 0.81 CHRM2 (0.59) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL245103 0.81 CHRM2 (0.59) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL11666746 0.78 CHRM1 (0.38) CHRM1
SCHEMBL17086736 0.78 SLC6A3 (0.50) KMT2ACYP2D6
SCHEMBL12846895 0.78 SLC6A3 (0.50) KMT2ACYP2D6
SCHEMBL17086732 0.78 SLC6A3 (0.50) KMT2ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104448451-A Thermoplastic elastomer composition YOKOHAMA RUBBER CO LTD 2015-03-25 CN claimed
CN-109535707-B Pneumatic tire 横滨橡胶株式会社 2021-05-25 CN disclosed
EP-2857451-B1 PNEUMATIC TIRE YOKOHAMA RUBBER CO LTD (JP) 2019-05-08 EP disclosed
US-10189980-B2 Process for producing thermoplastic resin composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2019-01-29 US disclosed
CN-105408413-B The manufacturing method of thermoplastic resin composition 横滨橡胶株式会社 2018-07-03 CN disclosed
US-9969873-B2 Pneumatic tire THE YOKOHAMA RUBBER CO., LTD. (JP) 2018-05-15 US disclosed
EP-2460851-B1 THERMOPLASTIC RESIN COMPOSITION YOKOHAMA RUBBER CO LTD (JP) 2017-09-20 EP disclosed
US-9580599-B2 Thermoplastic resin composition and tire using same THE YOKOHAMA RUBBER CO., LTD. (JP) 2017-02-28 US disclosed
US-9580582-B2 Thermoplastic resin composition and tire using same THE YOKOHAMA RUBBER CO., LTD. (JP) 2017-02-28 US disclosed
EP-2610311-B1 THERMOPLASTIC RESIN COMPOSITION AND TIRE USING SAME YOKOHAMA RUBBER CO LTD (JP) 2017-01-11 EP disclosed
EP-2174981-A1 Resin composition and multi-layer structures Kuraray Co., Ltd. (JP) 2010-04-14 EP disclosed
EP-1403289-B1 MODIFIED ETHYLENE -VINYL ALCOHOL COPOLYMER AND METHOD FOR THE PRODUCTION THEREOF KURARAY CO (JP) 2009-11-25 EP disclosed
US-7534829-B2 Resin composition and multi-layer structures KURARAY CO., LTD. (JP) 2009-05-19 US disclosed
US-7507476-B2 Multilayered pellet comprising ethylene-vinyl alcohol copolymer resin composition KURARAY CO., LTD. (JP) 2009-03-24 US disclosed
US-20070299194-A1 Multilayered Pellet Comprising Ethylene-Vinyl Alcohol Copolymer Resin Compositions KURARAY CO. LTD. (JP) 2007-12-27 US disclosed
EP-1785446-A1 MULTILAYERED PELLET COMPRISING ETHYLENE/VINYL ALCOHOL COPOLYMER RESIN COMPOSITIONS KURARAY CO., LTD. (JP) 2007-05-16 EP disclosed
US-20050147778-A1 Resin composition and multi-layer structures KURARAY CO., LTD. (JP) 2005-07-07 US disclosed
EP-1479725-A1 RESIN COMPOSITION AND MULTI-LAYER STRUCTURES Kuraray Co., Ltd. (JP) 2004-11-24 EP disclosed
US-20040096683-A1 Modified ethylene-vinyl alcohol copolymer and method for the production thereof KURARAY CO., LTD. (JP) 2004-05-20 US disclosed
EP-1403289-A1 MODIFIED ETHYLENE−VINYL ALCOHOL COPOLYMER AND METHOD FOR THE PRODUCTION THEREOF Kuraray Co., Ltd. (JP) 2004-03-31 EP disclosed