Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.44 |
| ▸ | MMP12 | P39900 | 2/20 | 0.43 |
| ▸ | MMP14 | P50281 | 13/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5096652 | 0.94 | MMP13 (0.41) | MMP13MMP12MMP14 | |
| SCHEMBL5097080 | 0.89 | MMP13 (0.46) | MMP13MMP12MMP14 | |
| SCHEMBL5249501 | 0.89 | MMP13 (0.46) | MMP13MMP12MMP14 | |
| SCHEMBL5090731 | 0.89 | MMP13 (0.44) | MMP13MMP12MMP14 | |
| SCHEMBL5103259 | 0.89 | MMP13 (0.48) | MMP13MMP12MMP14 | |
| SCHEMBL5103261 | 0.89 | MMP13 (0.48) | MMP13MMP12MMP14 | |
| SCHEMBL5253683 | 0.88 | MMP13 (0.44) | MMP13MMP12MMP14 | |
| SCHEMBL5103016 | 0.88 | MMP13 (0.44) | MMP13MMP12MMP14 | |
| SCHEMBL5241113 | 0.87 | MMP13 (0.43) | MMP13MMP12MMP14 | |
| SCHEMBL2289321 | 0.87 | MMP13 (0.43) | MMP13MMP12MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004317-A1 | Compounds | ASTRAZENECA AB (SE) | 2008-01-03 | — | — | US | claimed |
| US-20080004317-A1 | Compounds | ASTRAZENECA AB (SE) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004317-A1 | Compounds | CYP1A2, CYP2D6, F12 | MMP13 4291/4885MMP12 4485/4885MMP14 4794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.