Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 13/20 | 0.48 |
| ▸ | CA1 | P00915 | 11/20 | 0.48 |
| ▸ | CA5A | P35218 | 6/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.48 |
| ▸ | CA4 | P22748 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 9/20 | 0.40 |
| ▸ | CA7 | P43166 | 8/20 | 0.40 |
| ▸ | CA12 | O43570 | 7/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.40 |
| ▸ | CA6 | P23280 | 5/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 4/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CA11 | O75493 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2399941 | 0.98 | — | — | |
| Benzenesulfonamide SCHEMBL11048441 | 0.83 | CA2 (0.55) | CA2CA1CA5ACA5BCA4 | |
| SCHEMBL11800905 | 0.82 | CA2 (0.42) | CA2CA1CA5ACA5BCA4 | |
| SCHEMBL7481407 | 0.74 | — | — | |
| SCHEMBL9796194 | 0.64 | CA2 (0.71) | CA2CA1CA5ACA5BCA4 | |
| SCHEMBL29395571 | 0.62 | CA1 (0.40) | CA2CA1CA5ACA5BCA4 | |
| SCHEMBL41731 | 0.60 | — | — | |
| SCHEMBL3500987 | 0.60 | CA2 (0.95) | CA2CA1CA5ACA5BCA4 | |
| SCHEMBL3138923 | 0.59 | CA2 (0.40) | CA2CA1CA5ACA5BCA4 | |
| SCHEMBL276299 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1903873-A2 | HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS | THE UNIVERSITY OF ROCHESTER (US) | 2008-04-02 | — | — | EP | disclosed |
| WO-2006135602-A2 | HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS | UNIVERSITY OF ROCHESTER (US) | 2006-12-21 | — | — | WO | disclosed |