Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.55 |
| ▸ | CA1 | P00915 | 15/20 | 0.55 |
| ▸ | CA9 | Q16790 | 13/20 | 0.55 |
| ▸ | CA12 | O43570 | 12/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.55 |
| ▸ | CA5A | P35218 | 3/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.55 |
| ▸ | CA3 | P07451 | 2/20 | 0.55 |
| ▸ | CA6 | P23280 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.55 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2399941 | 0.85 | — | — | |
| SCHEMBL5097249 | 0.83 | CA2 (0.48) | CA2CA1CA9CA12CA14 | |
| Phenylthiourea SCHEMBL5490215 | 0.76 | ALDH1A1 (0.51) | CA2CA1CA9CA12CA5A | |
| Benzenesulfonamide SCHEMBL28257999 | 0.74 | CA2 (1.00) | CA2CA1CA9CA12CA14 | |
| Benzenesulfonamide SCHEMBL29825137 | 0.74 | CA2 (1.00) | CA2CA1CA9CA12CA14 | |
| Benzenesulfonamide SCHEMBL1332409 | 0.74 | CA2 (1.00) | CA2CA1CA9CA12CA14 | |
| Benzenesulfonamide SCHEMBL729 | 0.74 | CA2 (1.00) | CA2CA1CA9CA12CA14 | |
| SCHEMBL19479299 | 0.74 | CA2 (1.00) | CA2CA1CA9CA12CA14 | |
| Benzenesulfonamide SCHEMBL6868390 | 0.74 | CA2 (1.00) | CA2CA1CA9CA12CA14 | |
| Benzenesulfonamide SCHEMBL11798700 | 0.72 | CA2 (0.94) | CA2CA1CA9CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438123-A | Ophthalmic compositions of carbonic anhydrase inhibitors for topical application in the treatment of elevated intraocular pressure | MERCK & CO., INC. (US) | 1984-03-20 | — | — | US | claimed |