Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 18/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4064097 | 0.87 | DHPS (0.74) | DHPS | |
| SCHEMBL5097958 | 0.82 | KDM4E (0.42) | DHPSALDH1A1 | |
| SCHEMBL618135 | 0.76 | DHPS (0.58) | DHPS | |
| SCHEMBL29770374 | 0.76 | DHPS (0.58) | DHPS | |
| SCHEMBL13430565 | 0.74 | DHPS (0.43) | DHPS | |
| SCHEMBL12209056 | 0.74 | SMN1; SMN2 (0.42) | DHPSALDH1A1 | |
| SCHEMBL6490043 | 0.73 | KDM4E (0.39) | DHPSALDH1A1 | |
| SCHEMBL7209693 | 0.73 | DHPS (0.58) | DHPS | |
| SCHEMBL3227293 | 0.73 | DHPS (0.51) | DHPS | |
| SCHEMBL7795451 | 0.72 | DHPS (0.53) | DHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323465-B2 | Alkansulfonamides as endothelin antagonists | ACTELION PHARMACEUTICALS LTD. (CH) | 2008-01-29 | — | — | US | disclosed |