Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 14/20 | 0.58 |
| ▸ | EDNRA | P25101 | 6/20 | 0.46 |
| ▸ | EDNRB | P24530 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL618135 | 1.00 | DHPS (0.58) | DHPSEDNRAEDNRB | |
| SCHEMBL7795451 | 0.91 | DHPS (0.53) | DHPSEDNRAEDNRB | |
| SCHEMBL1257596 | 0.90 | DHPS (0.52) | DHPSEDNRAEDNRB | |
| SCHEMBL4064097 | 0.90 | DHPS (0.74) | DHPS | |
| SCHEMBL3227293 | 0.90 | DHPS (0.51) | DHPSEDNRAEDNRB | |
| SCHEMBL9423908 | 0.87 | LMNA (0.55) | DHPS | |
| SCHEMBL7300009 | 0.86 | DHPS (0.51) | DHPSEDNRA | |
| SCHEMBL4062097 | 0.86 | DHPS (0.51) | DHPSEDNRAEDNRB | |
| SCHEMBL13430565 | 0.85 | DHPS (0.43) | DHPSEDNRAEDNRB | |
| SCHEMBL7787027 | 0.85 | EDNRA (0.53) | DHPSEDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823052-A | Preparation method of bosentan | 致卓医药科技(北京)有限责任公司 | 2025-04-15 | — | — | CN | claimed |
| CN-114907275-A | Preparation method of bosentan | 武汉工程大学 | 2022-08-16 | — | — | CN | claimed |
| CN-119823052-B | Preparation method of bosentan | 致卓医药科技(北京)有限责任公司 | 2025-11-25 | — | — | CN | disclosed |
| CN-119823052-A | Preparation method of bosentan | 致卓医药科技(北京)有限责任公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-119823052-A | Preparation method of bosentan | 致卓医药科技(北京)有限责任公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-114605337-B | Preparation method of high-purity bosentan | 重庆医药高等专科学校 | 2024-03-12 | — | — | CN | disclosed |
| CN-114605337-B | Preparation method of high-purity bosentan | 重庆医药高等专科学校 | 2024-03-12 | — | — | CN | disclosed |
| CN-114907275-A | Preparation method of bosentan | 武汉工程大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-114907275-A | Preparation method of bosentan | 武汉工程大学 | 2022-08-16 | — | — | CN | disclosed |