Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.32 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604365 | 0.85 | MAP3K14 (0.32) | DYRK1ADYRK1BCHEK1MAP4K4CSF1R | |
| SCHEMBL4602967 | 0.76 | ALK (0.38) | DYRK1ADYRK1BCYP1A2CHEK1MAP4K4 | |
| SCHEMBL30973180 | 0.74 | MAPK8 (0.47) | FGFR1ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL1417158 | 0.72 | KDM4E (0.55) | ALDH1A1KMT2ADYRK1ADYRK1BCDK9 | |
| SCHEMBL5050800 | 0.72 | KCNJ1 (0.37) | FGFR1CYP2A6ALDH1A1KMT2ADYRK1A | |
| SCHEMBL9038736 | 0.69 | KDM4E (0.47) | ALDH1A1KMT2AMEN1DYRK1ADYRK1B | |
| SCHEMBL21038788 | 0.69 | CYP2A6 (0.42) | FGFR1CYP2A6ALDH1A1KMT2AMEN1 | |
| SCHEMBL3590167 | 0.68 | CYP2A6 (0.38) | CYP2A6ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL3411245 | 0.66 | CYP2A6 (0.50) | FGFR1CYP2A6ALDH1A1KMT2AMEN1 | |
| SCHEMBL557320 | 0.65 | ALDH1A1 (0.39) | CYP2A6ALDH1A1KMT2AMEN1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080261974-A1 | Novel Chemical Compounds | DUFFY KEVIN J | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261974-A1 | Novel Chemical Compounds | HIPK3, HIPK1, HIPK4 | FGFR1 3399/4885CYP2A6 4760/4885ALDH1A1 4004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.