Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 5/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.45 |
| ▸ | IDH2 | P48735 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5113542 | 0.89 | FABP4 (0.58) | FABP4FABP5IDH2SMN1; SMN2LMNA | |
| Trifluoroacetic Acid SCHEMBL5103243 | 0.89 | AKR1C3 (0.44) | IDH2SMN1; SMN2MAPTRAB9AAKR1C3 | |
| Trifluoroacetic Acid SCHEMBL5103915 | 0.86 | FABP4 (0.44) | FABP4FABP5IDH2SMN1; SMN2AKR1C3 | |
| Trifluoroacetic Acid SCHEMBL5099366 | 0.86 | CNR1 (0.45) | FABP4FABP5IDH2TP53AKR1C3 | |
| Trifluoroacetic Acid SCHEMBL5103755 | 0.85 | FFAR4 (0.44) | FABP4FABP5IDH2FFAR1FFAR4 | |
| Trifluoroacetic Acid SCHEMBL5100417 | 0.84 | FABP4 (0.45) | FABP4FABP5IDH2MAPTPDK1 | |
| Trifluoroacetic Acid SCHEMBL5107023 | 0.83 | IDH2 (0.45) | IDH2PDK1PDK2PDK3PDK4 | |
| Trifluoroacetic Acid SCHEMBL5113759 | 0.82 | KCNMA1 (0.45) | FABP4FABP5IDH2FFAR1FFAR4 | |
| SCHEMBL5113237 | 0.82 | FABP4 (0.41) | FABP4FABP5IDH2SMN1; SMN2MAPT | |
| Trifluoroacetic Acid SCHEMBL5103685 | 0.82 | MEN1 (0.44) | IDH2SMN1; SMN2RAB9ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249127-A1 | Muscarinic Acetylcholine Receptor Antagonists | LAINE DRAMANE I | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249127-A1 | Muscarinic Acetylcholine Receptor Antagonists | CHRM3, CHRNG, CHRM2 | FABP4 4255/4885FABP5 1382/4885IDH2 4016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.